Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. General Experimental Procedure
4.2. Fungus and Culture Conditions
4.3. Extraction and Isolation
4.4. Bioassay
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample Availability: Samples of the compounds 1–15 are available from the authors. |
Position | 1 | 2 | ||
---|---|---|---|---|
δH | δC | δH | δC | |
1 | 3.71 (dd, 12.0, 5.0) | 72.9 | 3.73 (dd, 12.0, 5.0) | 72.9 |
2 | 1.80 (m) | 27.3 | 1.72 (m) | 27.2 |
1.90 (m) | 1.93 (m) | |||
3 | 1.34 (m) | 37.7 | 1.37 (m) | 37.5 |
2.16 (m) | 2.17 (m) | |||
4 | - | 39.2 | - | 39.1 |
5 | 1.44 (d, 4.0) | 55.7 | 1.47 (d, 4.0) | 55.8 |
6 | - | 87.0 | - | 84.9 |
7 | 3.83 (dd, 11.5, 5.0) | 78.4 | 5.08 (dd, 11.5, 5.0) | 80.1 |
8 | 1.63 (m) | 28.9 | 1.44 (m) | 26.5 |
1.90 (m) | 1.84 (m) | |||
9 | 1.51 (dd, 12.5, 1.5) | 46.4 | 1.53 (d, 2.0) | 46.3 |
10 | - | 43.3 | - | 43.4 |
11 | 3.35 (d, 11.0) | 66.5 | 3.31 (d, 11.0) | 66.7 |
3.59 (d, 11.0) | 3.56 (d, 11.0) | |||
12 | 1.45 (s) | 18.0 | 1.45 (s) | 17.9 |
13 | 5.01 (d, 4.0) | 60.5 | 5.02 (d, 3.5) | 60.3 |
14 | 1.69 (s) | 16.0 | 1.79 (s) | 17.0 |
15 | 0.79 (s) | 12.7 | 0.79 (s) | 12.6 |
16 | - | - | - | 172.2 |
17 | - | - | 2.19 (s) | 21.2 |
18 | - | - | - | - |
19 | - | - | - | - |
2′ | - | 165.4 | - | 165.2 |
3′ | - | 104.4 | - | 104.5 |
4′ | - | 164.7 | - | 164.2 |
5′ | 6.86 (s) | 101.2 | 6.84 (s) | 101.1 |
6′ | - | 158.1 | - | 158.2 |
2″ | 9.07 (brs) | 147.4 | 9.08 (d, 2.0) | 147.4 |
3″ | - | 129.3 | - | 129.2 |
4″ | 8.32 (ddd, 8.0, 2.0, 1.5) | 134.9 | 8.33 (ddd, 8.0, 2.0, 1.5) | 134.9 |
5″ | 7.62 (dd, 8.0, 5.0) | 125.5 | 7.60 (dd, 8.0, 5.0) | 125.4 |
6″ | 8.69 (brd, 3.5) | 151.9 | 8.67 (dd, 5.0, 2.0) | 151.9 |
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Ying, Y.-M.; Huang, L.; Tian, T.; Li, C.-Y.; Wang, S.-L.; Ma, L.-F.; Shan, W.-G.; Wang, J.-W.; Zhan, Z.-J. Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method. Molecules 2018, 23, 2772. https://doi.org/10.3390/molecules23112772
Ying Y-M, Huang L, Tian T, Li C-Y, Wang S-L, Ma L-F, Shan W-G, Wang J-W, Zhan Z-J. Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method. Molecules. 2018; 23(11):2772. https://doi.org/10.3390/molecules23112772
Chicago/Turabian StyleYing, You-Min, Lu Huang, Ting Tian, Cui-Yu Li, Shi-Lei Wang, Lie-Feng Ma, Wei-Guang Shan, Jian-Wei Wang, and Zha-Jun Zhan. 2018. "Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method" Molecules 23, no. 11: 2772. https://doi.org/10.3390/molecules23112772