New Metabolites from Endophytic Fungus Chaetomium globosum CDW7
Abstract
:1. Introduction
2. Results and Discussion
2.1. Structure Elucidation
2.2. Biological Activity
3. Materials and Methods
3.1. General Experimental Procedures
3.2. The Source of Strains
3.3. Fermentation, Extraction, and Isolation
3.4. Antifungal Assays
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the compounds 1–5 are available from the authors. |
Position | δC | δH |
---|---|---|
1 | 166.2 | - |
3 | 151.8 | - |
4 | 104.3 | 6.15 (s) |
5 | 136.8 | - |
6 | 102.0 | 6.29 (s) |
7 | 161.3 | - |
8 | 110.4 | - |
9 | 161.3 | - |
9-OH | - | 11.42 (s) |
10 | 100.0 | - |
11 | 120.0 | 5.95 (dd, 0.8, 15.6) |
12 | 142.3 | 6.48 (dd, 8.1, 15.6) |
13 | 38.8 | 2.22 (m) |
14 | 29.4 | 1.42 (m) |
15 | 11.8 | 0.89 (t, 7.4) |
16 | 19.7 | 1.07 (d, 6.7) |
17 | 7.8 | 2.17 (s) |
Position | δC | δH |
---|---|---|
2 | 178.4 | - |
3 | 74.8 | - |
4a | 130.6 | - |
4 | 124.7 | 7.15 (s) |
5 | 137.4 | - |
6 | 130.1 | 7.05 (d, 7.8) |
7 | 110.7 | 6.77 (d, 7.8) |
7a | 138.6 | - |
8 | 48.8 | 2.98 (d, 17.1) |
3.16 (d, 17.1) | ||
9 | 207.9 | - |
10 | 31.6 | 2.17 (s) |
11 | 34.1 | 3.29 (d, 7.3) |
12 | 123.5 | 5.26 (t, 7.3) |
13 | 133.0 | - |
14 | 25.9 | 1.74 (s) |
15 | 17.9 | 1.70 (s) |
Pathogenic Fungi | 1 | 2 | 3 | 4 | 5 |
---|---|---|---|---|---|
S. sclerotiorum | 39.0 | 21.5 | 97.8 | 3.5 | 0.5 |
B. cinerea | 18.8 | 0 | 69.1 | 9.9 | 20.5 |
F. graminearum | 24.0 | 7.9 | 77.0 | 1.6 | 2.6 |
P. capsici | 13.7 | 8.5 | 60.7 | 6.6 | 8.6 |
F. moniliforme | 31.6 | 6.3 | 59.2 | 12.5 | 15.7 |
Compound | Treatment (μg/mL) | Diameter Lesion Length (mm) | Protective Efficacy (%) |
---|---|---|---|
3 | 200 | 12.5 ± 0.9 | 64.3 |
100 | 16.5 ± 1.2 | 45.2 | |
Carbendazim 2 | 200 | 11.5 ± 0.6 | 69.2 |
100 | 16.6 ± 0.5 | 44.6 | |
Negative control | - | 26.0 ± 1.4 | - |
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Share and Cite
Yan, W.; Cao, L.-L.; Zhang, Y.-Y.; Zhao, R.; Zhao, S.-S.; Khan, B.; Ye, Y.-H. New Metabolites from Endophytic Fungus Chaetomium globosum CDW7. Molecules 2018, 23, 2873. https://doi.org/10.3390/molecules23112873
Yan W, Cao L-L, Zhang Y-Y, Zhao R, Zhao S-S, Khan B, Ye Y-H. New Metabolites from Endophytic Fungus Chaetomium globosum CDW7. Molecules. 2018; 23(11):2873. https://doi.org/10.3390/molecules23112873
Chicago/Turabian StyleYan, Wei, Ling-Ling Cao, Yang-Yang Zhang, Ran Zhao, Shuang-Shuang Zhao, Babar Khan, and Yong-Hao Ye. 2018. "New Metabolites from Endophytic Fungus Chaetomium globosum CDW7" Molecules 23, no. 11: 2873. https://doi.org/10.3390/molecules23112873