Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3’Z)-3,3’-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives
Abstract
:1. Introduction
2. Results
2.1. Chemical Synthesis and Characterisation
2.2. Computational Studies
3. Conclusions
4. Experimental Section
4.1. General Methods
4.2. Synthesis and Characterisation
4.2.1. General procedure for the synthesis of 7
4.2.2. General procedure for the synthesis of 6
4.3. Computational Method
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample Availability: Samples of the compounds 3, 5, 7a–d, and 7f–i are available from the authors. |
Entry | Compound | R | Yield % |
---|---|---|---|
1 | 7a | propyl | 58 |
2 | 7b | isopropyl | 57 |
3 | 7c | ethyl | 59 |
4 | 7d | methyl | 60 |
5 | 7e | 57 | |
6 | 7f | 53 | |
7 | 7g | 54 | |
8 | 7h | 56 | |
9 | 7i | 52 1 |
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Khalili, G.; McCosker, P.M.; Clark, T.; Keller, P.A. Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3’Z)-3,3’-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives. Molecules 2019, 24, 3649. https://doi.org/10.3390/molecules24203649
Khalili G, McCosker PM, Clark T, Keller PA. Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3’Z)-3,3’-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives. Molecules. 2019; 24(20):3649. https://doi.org/10.3390/molecules24203649
Chicago/Turabian StyleKhalili, Gholamhossein, Patrick M. McCosker, Timothy Clark, and Paul A. Keller. 2019. "Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3’Z)-3,3’-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives" Molecules 24, no. 20: 3649. https://doi.org/10.3390/molecules24203649