Taste Processing: Insights from Animal Models
Abstract
:1. Introduction
2. Taste System
3. Taste Learning
3.1. Conditioned Taste Aversion: A Peculiar Taste Learning
3.2. Neural Network of CTA
3.3. Molecular Mechanisms of CTA
4. Conclusions
Funding
Conflicts of Interest
References
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Receptors | Protein Expression | Molecular Signals |
---|---|---|
NMDAr (GIC; CTA acquisition and taste learning) [56,75,76,77] AMPAr (GIC; CTA acquisition) [56,75,76] GluR2 (amygdala and PEC; SP and taste memory) [78] mACh (GIC; neophobia, SP and CTA acquisition) [56,75,76,79,80,81] DA (GIC; novel taste memory) [76,82] GABA-A (GIC; taste recognition) [56,75,76,80,81] NR1 (PFC; SP in CTA acquisition) [44] NR2A-2B (GIC; CTA acquisition and taste processing) [83] TrkB (GIC; taste memory) [78] β-adrenergic (GIC; novel taste memory) [82] D1 (GIC; novel taste processing and memory) [84] | c-fos (GIC; SP and LT taste memory) [72] BDNF (GIC and amygdala; SP in taste memory and CTA) [71,78,85,86] Homer 1a (GIC; SP and LT taste memory) [73] Arc/Arg3.1 (GIC; CTA memory) [60,68,69,70] Transcription factor Elk-1 (GIC; SP and LT taste memory) [74] | cAMP (GIC; SP and taste memory) [76] Adenylyl cyclase (GIC; SP and taste memory) [76] Actin (IFC; structural plasticity and CTA memory) [87] PKA (GIC and amygdala CTA memory) [76,88] CaMKIIα (GIC; SP, novel taste memory, CTA acquisition) [89] PKC (GIC and amygdala; LT plasticity and CTA memory) [76,88] NSF (amygdala and PEC; SP and taste memory) [90] ERK1/2 (GIC; novel taste processing, SP and taste memory) [82,84] Myosin II (IFC; structural plasticity and CTA memory) [87] PSD-95 (GIC; SP and taste learning) [64,77] PI3K (GIC; SP and CTA memory) [91] |
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Molero-Chamizo, A.; Rivera-Urbina, G.N. Taste Processing: Insights from Animal Models. Molecules 2020, 25, 3112. https://doi.org/10.3390/molecules25143112
Molero-Chamizo A, Rivera-Urbina GN. Taste Processing: Insights from Animal Models. Molecules. 2020; 25(14):3112. https://doi.org/10.3390/molecules25143112
Chicago/Turabian StyleMolero-Chamizo, Andrés, and Guadalupe Nathzidy Rivera-Urbina. 2020. "Taste Processing: Insights from Animal Models" Molecules 25, no. 14: 3112. https://doi.org/10.3390/molecules25143112