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Review

Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles

1
Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Deanship of Research Development, Prince Mohammad Bin Fahd University, Al Khobar 31952, Saudi Arabia
2
Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh 174301, India
*
Author to whom correspondence should be addressed.
Molecules 2020, 25(24), 5918; https://doi.org/10.3390/molecules25245918
Submission received: 25 August 2020 / Revised: 21 September 2020 / Accepted: 23 September 2020 / Published: 14 December 2020
(This article belongs to the Special Issue Halogen-Controlled Synthesis of Useful Organic Molecules)

Abstract

During the last two decades, tetrabutylammonium bromide (TBAB) has gained significant attention as an efficient metal-free homogeneous phase-transfer catalyst. A catalytic amount of TBAB is sufficient to catalyze various alkylation, oxidation, reduction, and esterification processes. It is also employed as an efficient co-catalyst for numerous coupling reactions. It has also acted as an efficient zwitterionic solvent in many organic transformations under molten conditions. In this review, we have summarized the recent developments on TBAB-catalyzed protocols for the efficient synthesis of various biologically promising heterocyclic scaffolds.
Keywords: tetrabutylammonium bromide; TBAB; phase-transfer catalyst; metal-free synthesis; bioactive heterocycles tetrabutylammonium bromide; TBAB; phase-transfer catalyst; metal-free synthesis; bioactive heterocycles
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MDPI and ACS Style

Banik, B.K.; Banerjee, B.; Kaur, G.; Saroch, S.; Kumar, R. Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles. Molecules 2020, 25, 5918. https://doi.org/10.3390/molecules25245918

AMA Style

Banik BK, Banerjee B, Kaur G, Saroch S, Kumar R. Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles. Molecules. 2020; 25(24):5918. https://doi.org/10.3390/molecules25245918

Chicago/Turabian Style

Banik, Bimal Krishna, Bubun Banerjee, Gurpreet Kaur, Shivam Saroch, and Rajat Kumar. 2020. "Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles" Molecules 25, no. 24: 5918. https://doi.org/10.3390/molecules25245918

APA Style

Banik, B. K., Banerjee, B., Kaur, G., Saroch, S., & Kumar, R. (2020). Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles. Molecules, 25(24), 5918. https://doi.org/10.3390/molecules25245918

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