Fluorescent Azasteroids through Ultrasound Assisted Cycloaddition Reactions
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental Section
3.1. General Procedure
3.1.1. General Procedure for Synthesis of Azasteroids Derivatives, 5a–b, 7a–b and 8c under Conventional TH Conditions
3.1.2. General Procedure for Synthesis of Azasteroids Derivatives, 5a–b, 7a–b and 8c under US Irradiation
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Sample Availability
References
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Compound Data Availability Statement | Ultrasounds | Conventional TH | |||
---|---|---|---|---|---|
Reaction Time, (h) | Yield, % | Reaction Time, (h) | Yield, % | ||
5a | 2 | 80 | 48 | 65 | |
5b | 81 | 69 | |||
5c | 78 | 64 | |||
7a | 71 | 54 | |||
7b | 69 | 54 | |||
7c | 65 | 38 | |||
8c | 5 | 13 |
Compound | Fluorescence (λmax, nm) | Absorption (λmax, nm) | ||
---|---|---|---|---|
Cyclohexane | Trichloromethane | Cyclohexane | Trichloromethane | |
5a | 434 | 439 | 399 | 403 |
5b | 434 | 440 | 399 | 402 |
5c | 440 | 445 | 384 | 386 |
7a | 432 | 432 | 378 | 381 |
7b | 432 | 433 | 376 | 375 |
7c | 451 | 430 | 373 | 370 |
8c | 450 | 449 | 374 | 369 |
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Moldoveanu, C.; Mangalagiu, I.; Zbancioc, G. Fluorescent Azasteroids through Ultrasound Assisted Cycloaddition Reactions. Molecules 2021, 26, 5098. https://doi.org/10.3390/molecules26165098
Moldoveanu C, Mangalagiu I, Zbancioc G. Fluorescent Azasteroids through Ultrasound Assisted Cycloaddition Reactions. Molecules. 2021; 26(16):5098. https://doi.org/10.3390/molecules26165098
Chicago/Turabian StyleMoldoveanu, Costel, Ionel Mangalagiu, and Gheorghita Zbancioc. 2021. "Fluorescent Azasteroids through Ultrasound Assisted Cycloaddition Reactions" Molecules 26, no. 16: 5098. https://doi.org/10.3390/molecules26165098