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Article

Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth

by
Paulo Wender P. Gomes
1,2,
Hugo Barretto
2,
José Diogo E. Reis
2,
Abraão Muribeca
2,
Alice Veloso
2,
Carlos Albuquerque
2,
Andrew Teixeira
3,
Wandson Braamcamp
2,
Sônia Pamplona
2,
Consuelo Silva
2,4 and
Milton Silva
2,*
1
Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA
2
Laboratory of Liquid Chromatography (Labcrol), Institute of Exact and Natural Sciences, Federal Universityof Pará, Belém 66075-110, Brazil
3
Department of Natural Sciences, Faculty of Chemistry, Campus Barcarena, State University of Pará, R. Tomás Lourenço Fernandes, Barcarena 68445-000, Brazil
4
Faculty of Pharmaceutical Sciences, Federal University of Pará, Belém 66075-110, Brazil
*
Author to whom correspondence should be addressed.
Molecules 2022, 27(6), 1847; https://doi.org/10.3390/molecules27061847
Submission received: 31 December 2021 / Revised: 20 January 2022 / Accepted: 26 January 2022 / Published: 11 March 2022
(This article belongs to the Special Issue Discovery of Bioactive Ingredients from Natural Products, 2nd Edition)
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Abstract

Peperomia pellucida is a species known in the Amazon as “erva-de-jabuti” that has been used in several therapeutic applications based on folk medicine. Herein, we describe the classes, subclasses, and the main compounds of the leaves, stems, and roots from P. pellucida by ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry associated with molecular networks, mirror plot on the GNPS library, and machine learning. These data show compounds that were annotated for the first time in the Peperomia genus, such as 2′,4′,5′-trihydroxybutyrophenonevelutin, dehydroretrofractamide C, and retrofractamide B.
Keywords: Piperaceae; LC-MS/MS; molecular network; machine learning; Sirius Piperaceae; LC-MS/MS; molecular network; machine learning; Sirius

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MDPI and ACS Style

Gomes, P.W.P.; Barretto, H.; Reis, J.D.E.; Muribeca, A.; Veloso, A.; Albuquerque, C.; Teixeira, A.; Braamcamp, W.; Pamplona, S.; Silva, C.; et al. Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth. Molecules 2022, 27, 1847. https://doi.org/10.3390/molecules27061847

AMA Style

Gomes PWP, Barretto H, Reis JDE, Muribeca A, Veloso A, Albuquerque C, Teixeira A, Braamcamp W, Pamplona S, Silva C, et al. Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth. Molecules. 2022; 27(6):1847. https://doi.org/10.3390/molecules27061847

Chicago/Turabian Style

Gomes, Paulo Wender P., Hugo Barretto, José Diogo E. Reis, Abraão Muribeca, Alice Veloso, Carlos Albuquerque, Andrew Teixeira, Wandson Braamcamp, Sônia Pamplona, Consuelo Silva, and et al. 2022. "Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth" Molecules 27, no. 6: 1847. https://doi.org/10.3390/molecules27061847

APA Style

Gomes, P. W. P., Barretto, H., Reis, J. D. E., Muribeca, A., Veloso, A., Albuquerque, C., Teixeira, A., Braamcamp, W., Pamplona, S., Silva, C., & Silva, M. (2022). Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth. Molecules, 27(6), 1847. https://doi.org/10.3390/molecules27061847

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