Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole
Abstract
:1. Introduction
2. Results and Discussion
3. Materials and Methods
3.1. General
3.2. 6-(Benzyloxy)-5,7-dimethyloxazolo[4,5-b]pyridin-2-amine (23)
3.3. 2-Amino-5,7-dimethyloxazolo[4,5-b]pyridin-6-ol (12)
3.4. 6-Benzyloxy-5,7-dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one (27)
3.5. 5-Amino-3-(benzyloxy)-2,4-dimethylpyridine 1-oxide (28)
3.6. 2-(3-Amino-5-(benzyloxy)-4,6-dimethylpyridin-2-yl)isoindoline-1,3-dione (29)
3.7. 5-(Benzyloxy)-4,6-dimethylpyridine-2,3-diamine (20)
3.8. 6-(Benzyloxy)-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-2-amine (30)
3.9. 2-Amino-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-6-ol hydrochloride (13)
3.10. 3-(Benzyloxy)-5-(cyanomethyl)-2,4-dimethylpyridine 1-oxide (34)
3.11. 2-(5-(Benzyloxy)-2-(1,3-dioxoisoindolin-2-yl)-4,6-dimethylpyridin-3-yl)acetonitrile (35)
3.12. 2-(2-Amino-5-(benzyloxy)-4,6-dimethylpyridin-3-yl)acetonitrile (36)
3.13. Methyl 2-amino-5-(benzyloxy)-4,6-dimethylnicotinate (44)
3.14. N-(5-(benzyloxy)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridin-2-yl)acetamide (45)
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Sample Availability
References
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Awasthi, B.P.; Lee, H.; Jeong, B.-S. Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole. Molecules 2022, 27, 2075. https://doi.org/10.3390/molecules27072075
Awasthi BP, Lee H, Jeong B-S. Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole. Molecules. 2022; 27(7):2075. https://doi.org/10.3390/molecules27072075
Chicago/Turabian StyleAwasthi, Bhuwan Prasad, Hyunji Lee, and Byeong-Seon Jeong. 2022. "Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole" Molecules 27, no. 7: 2075. https://doi.org/10.3390/molecules27072075