Antifungal Sesquiterpenoids from Michelia formosana Leaf Essential Oil against Wood-Rotting Fungi
Abstract
:1. Introduction
2. Results and Discussion
2.1. Antifungal Activities of M. formosana Leaf Essential Oil and Its Fractions
2.2. Isolation and Identification of Constituents from M. formosana Leaf Essential Oil
2.3. Antifungal Effect of Sesquiterpenoids from M. formosana Leaf Essential Oil
3. Materials and Methods
3.1. Plant Materials
3.2. Hydrodistillation of Leaf Essential Oil
3.3. Antifungal Assay
3.4. Bioassay-Guided Isolation by Various Chromatographies
3.5. Structural Elucidation
3.6. Statistical Analysis
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Sample Availability
References
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Fungus | Antifungal Index (%) | |
---|---|---|
100 μg/mL | 500 μg/mL | |
L. sulphureus | 67.44 ± 3.29 b | 100.00 ± 0.00 a |
L. betulina | 25.97 ± 0.67 c | 94.19 ± 1.16 a |
Specimen | IC50 (μg/mL) | |
---|---|---|
L. Sulphureus | L. Betulina | |
DDAC * | 0.37 ± 0.03 c ** (<0.01) *** | 3.24 ± 0.11 C (0.01 ± 0.00) |
4,5-Epoxy-β-caryophyllene | >100 | >100 |
Guaiol | 30.7 ± 2.8 a (0.14 ± 0.01) | 44.1 ± 1.6 B (0.20 ± 0.01) |
Bulnesol | 23.1 ± 0.9 b (0.10 ± 0.00) | 60.2 ± 2.6 A (0.27 ± 0.01) |
β-Elemol | 30.5 ± 2.3 a (0.14 ± 0.01) | 40.5 ± 2.4 B (0.18 ± 0.01) |
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Wu, C.-C.; Huang, S.-L.; Ko, C.-H.; Chang, H.-T. Antifungal Sesquiterpenoids from Michelia formosana Leaf Essential Oil against Wood-Rotting Fungi. Molecules 2022, 27, 2136. https://doi.org/10.3390/molecules27072136
Wu C-C, Huang S-L, Ko C-H, Chang H-T. Antifungal Sesquiterpenoids from Michelia formosana Leaf Essential Oil against Wood-Rotting Fungi. Molecules. 2022; 27(7):2136. https://doi.org/10.3390/molecules27072136
Chicago/Turabian StyleWu, Chia-Che, Shou-Ling Huang, Chun-Han Ko, and Hui-Ting Chang. 2022. "Antifungal Sesquiterpenoids from Michelia formosana Leaf Essential Oil against Wood-Rotting Fungi" Molecules 27, no. 7: 2136. https://doi.org/10.3390/molecules27072136