Influence of a Composite Polylysine-Polydopamine-Quaternary Ammonium Salt Coating on Titanium on Its Ostogenic and Antibacterial Performance
Abstract
:1. Introduction
2. Results and Discussion
2.1. Wettability of Surfaces
2.2. Surface Roughness
2.3. Surface Composition
2.4. Molar Grafting Rate
2.5. Cell Compatibility
2.6. Antibacterial Performance
3. Materials and Methods
3.1. Materials
3.2. Preparation of Collagen Peptide Solution
3.3. Preparation of Polylysine-Polydopamine-Quaternary Ammonium Salt Composite Coating
3.4. Determination of UV-Visible Spectra
3.5. Determination of WCA
3.6. AFM Characterization
3.7. X-ray Photoelectron Spectroscopy (XPS)
3.8. Molar Grafting Rate
3.9. Cell Compatibility Determination
3.10. Antibacterial Performance Determination
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Sample Availability
References
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Sample | QAS | ||||
---|---|---|---|---|---|
EPTAC | DEQAS | MPA-N+ | DEQAS/MPA-N+ | ||
DEQAS | MPA-N+ | ||||
pTi-(PLL-PDA)1 | 4.074 | 3.732 | 4.936 | 4.839 (±0.001) | 1.862 (±0.001) |
pTi-(PLL-PDA)5 | 5.752 | 4.573 | 4.830 | 5.109 (±0.001) | 1.959 (±0.001) |
pTi-(PLL-PDA)10 | 7.103 | 6.291 | 5.138 | 7.480 (±0.001) | 3.162 (±0.001) |
pTi-(PLL-PDA)15 | 7.940 | 6.493 | 5.392 | 7.529 (±0.001) | 3.257 (±0.001) |
Study Group | Properties Determined | |||
---|---|---|---|---|
WCA | Grafting Rate | Cell Viability | Kill% | |
As-received, uncoated Ti | + | + | + | |
Porous Ti (pTi) | + | |||
pTi-PLL | + | |||
pTi-(PLL-PDA)1 | + | |||
pTi-(PLL-PDA)2 | + | |||
pTi-(PLL-PDA)5 | + | |||
pTi-(PLL-PDA)10 | + | |||
pTi-(PLL-PDA)15 | + | |||
pTi-(PLL-PDA)1-EPTAC | + | |||
pTi-(PLL-PDA)1-DEQAS | + | |||
pTi-(PLL-PDA)1-(MPA-N+) | + | |||
pTi-(PLL-PDA)1-(MPA-N+)/DEQAS | + | |||
pTi-(PLL-PDA)5-EPTAC | + | |||
pTi-(PLL-PDA)5-DEQAS | + | |||
pTi-(PLL-PDA)5-(MPA-N+) | + | |||
pTi-(PLL-PDA)5-(MPA-N+)/DEQAS | + | |||
pTi-(PLL-PDA)10-EPTAC | + | |||
pTi-(PLL-PDA)10-DEQAS | + | |||
pTi-(PLL-PDA)10-(MPA-N+) | + | |||
pTi-(PLL-PDA)10-(MPA-N+)/DEQAS | + | |||
pTi-(PLL-PDA)15-EPTAC | + | + | ||
pTi-(PLL-PDA)15-DEQAS | + | + | + | |
pTi-(PLL-PDA)15-(MPA-N+) | + | + | + | |
pTi-(PLL-PDA)15-(MPA-N+)/DEQAS | + | + | + |
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Xing, L.; Song, H.; Wei, J.; Wang, X.; Yang, Y.; Zhe, P.; Luan, M.; Xu, J. Influence of a Composite Polylysine-Polydopamine-Quaternary Ammonium Salt Coating on Titanium on Its Ostogenic and Antibacterial Performance. Molecules 2023, 28, 4120. https://doi.org/10.3390/molecules28104120
Xing L, Song H, Wei J, Wang X, Yang Y, Zhe P, Luan M, Xu J. Influence of a Composite Polylysine-Polydopamine-Quaternary Ammonium Salt Coating on Titanium on Its Ostogenic and Antibacterial Performance. Molecules. 2023; 28(10):4120. https://doi.org/10.3390/molecules28104120
Chicago/Turabian StyleXing, Lei, Hongyang Song, Jinjian Wei, Xue Wang, Yaozhen Yang, Pengbo Zhe, Mingming Luan, and Jing Xu. 2023. "Influence of a Composite Polylysine-Polydopamine-Quaternary Ammonium Salt Coating on Titanium on Its Ostogenic and Antibacterial Performance" Molecules 28, no. 10: 4120. https://doi.org/10.3390/molecules28104120