Phytochemicals, Two New Sulphur Glycosides and Two New Natural Products, from Shepherd’s Purse Seed and Their Activities
Abstract
:1. Introduction
2. Results
2.1. Structure Elucidation
2.2. Structural Information of 1–2
2.3. Proposed Biosynthetic Pathway
2.4. Anti-Radiation Activity
2.5. Molecular Docking Analysis
3. Materials and Methods
3.1. General Experimental Procedures
3.2. Plant Materials
3.3. Isolations of Compounds
3.4. Cells and Cell Culture
3.5. Anti-Radiation Assay
3.6. Molecular Docking Assay
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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No | Compond 3 (CD3OD) | Compond 4 (DMSO-d6) | ||
---|---|---|---|---|
δH (J in Hz) | δc | δH (J in Hz) | δc | |
1 | - | 179.2 | - | 177.7 |
2 | 2.29 (2H, t, 7.3) | 37.3 | 2.27 (2H, m) | 35.2 |
3 | 1.61 (2H, m) | 26.9 | 1.51 (2H, m) | 25.2 |
4 | 1.32–1.38 (2H, m) | 29.7 | 1.24–1.30 (2H, m) | 28.4 |
5 | 1.32–1.38 (2H, m) | 30.2 | 1.24–1.30 (2H, m) | 28.6 |
6 | 1.32–1.38 (2H, m) | 30.3 | 1.24–1.30 (2H, m) | 28.8 |
7 | 1.32–1.38 (2H, m) | 30.4 | 1.24–1.30 (2H, m) | 28.7 |
8 | 1.32–1.38 (2H, m) | 30.4 | 1.24–1.30 (2H, m) | 28.4 |
9 | 1.48 (2H, m) | 30.2 | 1.37 (2H, m) | 28.1 |
10 | 1.75 (2H, m) | 23.6 | 1.61 (2H, m) | 21.9 |
11 | 2.80 (2H, m) | 54.9 | 2.73 (1H, m) 2.62 (1H, m) | 53.2 |
CH3SO | 2.63 (3H, s) | 38.1 | 2.50 (3H, s) | 38.0 |
1′ | 5.43 (1H, d, 5.8) | 90.3 | 4.12 (1H, d, 9.4) | 88.9 |
2′ | 3.75 (1H, dd, 5.8, 3.9) | 73.1 | 2.99 (1H, m) | 70.2 |
3′ | 4.07 (1H, m) | 74.6 | 2.86 (1H, m) | 70.1 |
4′ | 3.37 (1H, t, 9.9) | 71.2 | 3.19 (1H, m) | 76.6 |
5′ | 3.49 (1H, t, 9.3) | 75.8 | 3.24 (1H, m) | 81.5 |
6′ | 3.78 (1H, dd, 11.8, 2.5) 3.74 (1H, dd, 11.0, 5.1) | 62.4 | 3.69 (1H, dd, 11.8, 5.4) 3.41 (1H, m) | 61.3 |
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Wei, Z.-Z.; Ge, C.-B.; Wang, Y.-J.; Li, B.; Tian, Y.; Zhou, T.-Q.; Liu, S.-C.; Yi, J.-F. Phytochemicals, Two New Sulphur Glycosides and Two New Natural Products, from Shepherd’s Purse Seed and Their Activities. Molecules 2024, 29, 4145. https://doi.org/10.3390/molecules29174145
Wei Z-Z, Ge C-B, Wang Y-J, Li B, Tian Y, Zhou T-Q, Liu S-C, Yi J-F. Phytochemicals, Two New Sulphur Glycosides and Two New Natural Products, from Shepherd’s Purse Seed and Their Activities. Molecules. 2024; 29(17):4145. https://doi.org/10.3390/molecules29174145
Chicago/Turabian StyleWei, Zhen-Zhen, Chun-Bo Ge, Yu-Jie Wang, Bin Li, Ying Tian, Ti-Qiang Zhou, Shu-Chen Liu, and Jian-Feng Yi. 2024. "Phytochemicals, Two New Sulphur Glycosides and Two New Natural Products, from Shepherd’s Purse Seed and Their Activities" Molecules 29, no. 17: 4145. https://doi.org/10.3390/molecules29174145