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Review

Amino Acid-Derived Supramolecular Assembly and Soft Materials

by
Shuaishuai Nie
1,
He Zhao
1,
Jiayi Sun
1,
Qingtao Liu
2,*,
Yongming Cui
2 and
Wen Li
1,*
1
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China
2
National Local Joint Engineering Laboratory for Advanced Textile Processing and Clean Production, Wuhan Textile University, Wuhan 430200, China
*
Authors to whom correspondence should be addressed.
Molecules 2024, 29(19), 4705; https://doi.org/10.3390/molecules29194705
Submission received: 3 September 2024 / Revised: 30 September 2024 / Accepted: 2 October 2024 / Published: 4 October 2024
(This article belongs to the Special Issue Molecular Self-Assembly in Interfacial Chemistry)

Abstract

Amino acids (AAs), serving as the primary monomer of peptides and proteins, are widely present in nature. Benefiting from their inherent advantages, such as chemical diversity, low cost, ease of modification, chirality, biosafety, and bio-absorbability, AAs have been extensively exploited to create self-assembled nanostructures and supramolecular soft materials. In this review article, we systematically describe the recent progress regarding amino acid-derived assembly and functional soft materials. A brief background and several classified assemblies of AAs and their derivatives (chemically modified AAs) are summarized. The key non-covalent interactions to drive the assembly of AAs are emphasized based on the reported systems of self-assembled and co-assembled AAs. We discuss the molecular design of AAs and the general rules behind the hierarchical nanostructures. The resulting soft materials with interesting properties and potential applications are demonstrated. The conclusion and remarks on AA-based supramolecular assemblies are also presented from the viewpoint of chemistry, materials, and bio-applications.
Keywords: amino acids; supramolecular assembly; nanostructures; soft materials amino acids; supramolecular assembly; nanostructures; soft materials

Share and Cite

MDPI and ACS Style

Nie, S.; Zhao, H.; Sun, J.; Liu, Q.; Cui, Y.; Li, W. Amino Acid-Derived Supramolecular Assembly and Soft Materials. Molecules 2024, 29, 4705. https://doi.org/10.3390/molecules29194705

AMA Style

Nie S, Zhao H, Sun J, Liu Q, Cui Y, Li W. Amino Acid-Derived Supramolecular Assembly and Soft Materials. Molecules. 2024; 29(19):4705. https://doi.org/10.3390/molecules29194705

Chicago/Turabian Style

Nie, Shuaishuai, He Zhao, Jiayi Sun, Qingtao Liu, Yongming Cui, and Wen Li. 2024. "Amino Acid-Derived Supramolecular Assembly and Soft Materials" Molecules 29, no. 19: 4705. https://doi.org/10.3390/molecules29194705

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