The High-Precision Liquid Chromatography with Electrochemical Detection (HPLC-ECD) for Monoamines Neurotransmitters and Their Metabolites: A Review

Bruno P Guiard is a Professor at the University of Toulouse. He completed his Master’s degree in Neuroscience back in 2001 and then joined the Neuro-Gastroenterology unit (INRA, Toulouse, France) to conduct his first in vivo experiments. His research focused on the neurophysiology of pain. In 2003, he received a research grant from the French Ministry of Research and moved to the University of Paris XI (Faculty of Pharmacy). From 2003 to 2005, he worked on the effects of tachykinins in the modulation of central serotonin transmission by using in vivo microdialysis. He earned his Ph.D. in Neuropharmacology in 2005 and was awarded for his thesis the same year. From 2005 to 2007, Dr. Guiard went to North America as a post-doc fellow at the Institute of Mental Health Research. There, he continued his work in the field of mood disorders and antidepressants, specifically exploring the functional interaction between dopamine, serotonin, and norepinephrine neurons using electrophysiology. In 2007, he joined the Department of Neuropharmacology in Professor A. Gardier’s lab (University of Paris) as an associate professor, where he divided his time between teaching and research. In 2019, he obtained a position as a regular Professor at the University of Toulouse. Dr. Guiard’s current investigations aim to better understand the influence of psychedelic substances on the modulation of monoaminergic neurotransmissions and brain-related functions.