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Review

Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles

by
Yue Zhuo
1,
Yong-Gang Zhao
2,* and
Yun Zhang
3,*
1
School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 511442, China
2
College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China
3
School of Materials Science and Engineering, NingboTech University, Ningbo 315100, China
*
Authors to whom correspondence should be addressed.
Molecules 2024, 29(20), 4854; https://doi.org/10.3390/molecules29204854
Submission received: 6 September 2024 / Revised: 9 October 2024 / Accepted: 11 October 2024 / Published: 13 October 2024
(This article belongs to the Special Issue Advances in Targeted Delivery of Nanomedicines)
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Abstract

Biological variability poses significant challenges in the development of effective therapeutics, particularly when it comes to drug solubility and bioavailability. Poor solubility across varying physiological conditions often leads to reduced absorption and inconsistent therapeutic outcomes. This review examines how nanotechnology, especially through the use of nanomaterials and magnetic nanoparticles, offers innovative solutions to enhance drug solubility and bioavailability. This comprehensive review focuses on recent advancements and approaches in nanotechnology. We highlight both the successes and remaining challenges in this field, emphasizing the role of continued innovation. Future research should prioritize developing universal therapeutic solutions, conducting interdisciplinary research, and leveraging personalized nanomedicine to address biological variability.
Keywords: biological variability; nanotechnology; magnetic nanoparticles; drug absorption; drug solubility; targeted drug delivery; therapeutic efficacy; drug design biological variability; nanotechnology; magnetic nanoparticles; drug absorption; drug solubility; targeted drug delivery; therapeutic efficacy; drug design

Share and Cite

MDPI and ACS Style

Zhuo, Y.; Zhao, Y.-G.; Zhang, Y. Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles. Molecules 2024, 29, 4854. https://doi.org/10.3390/molecules29204854

AMA Style

Zhuo Y, Zhao Y-G, Zhang Y. Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles. Molecules. 2024; 29(20):4854. https://doi.org/10.3390/molecules29204854

Chicago/Turabian Style

Zhuo, Yue, Yong-Gang Zhao, and Yun Zhang. 2024. "Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles" Molecules 29, no. 20: 4854. https://doi.org/10.3390/molecules29204854

APA Style

Zhuo, Y., Zhao, Y.-G., & Zhang, Y. (2024). Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles. Molecules, 29(20), 4854. https://doi.org/10.3390/molecules29204854

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