Practical and Efficient Procedure for the In Situ Preparation of B-Alkoxyoxazaborolidines. Enantioselective Reduction of Prochiral Ketones
Abstract
:Product | B-alkoxy-OAB | ee(%) | Yield (%) |
R-1-(3,4-dimethoxyphenyl)ethanol | 1a-7a | >95 | >93 |
R-1-(4-acetoxy-3-methoxyphenyl)ethanol | 5a | 97 | ≈100 |
R-1-(4-hydroxy-3-methoxyphenyl)ethanol | 6a | >98 | 98 |
R-1-(2,4-dimethoxyphenyl)ethanol | 6a | 90 | ≈100 |
R-1(4-nitrophenyl)ethanol | 6a | >95 | ≈100 |
R-1(4-aminophenyl)ethanol | 6a | 95 | ≈100 |
R-1(4-bromophenyl)ethanol | 6a | 97 | 98 |
Acknowledgements
References and Notes
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Ponzo, V.L.; Kaufman, T.S. Practical and Efficient Procedure for the In Situ Preparation of B-Alkoxyoxazaborolidines. Enantioselective Reduction of Prochiral Ketones. Molecules 2000, 5, 495-496. https://doi.org/10.3390/50300495
Ponzo VL, Kaufman TS. Practical and Efficient Procedure for the In Situ Preparation of B-Alkoxyoxazaborolidines. Enantioselective Reduction of Prochiral Ketones. Molecules. 2000; 5(3):495-496. https://doi.org/10.3390/50300495
Chicago/Turabian StylePonzo, Viviana L., and Teodoro S. Kaufman. 2000. "Practical and Efficient Procedure for the In Situ Preparation of B-Alkoxyoxazaborolidines. Enantioselective Reduction of Prochiral Ketones" Molecules 5, no. 3: 495-496. https://doi.org/10.3390/50300495