RETRACTED: miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2
Abstract
:1. Introduction
2. Results
2.1. miR-126 Was under-Expressed in OS Tissues and OS Cell Lines
2.2. miR-126 Functions as a Tumor Suppressor in MG-63 Cells
2.3. miR-126 Targets Sox2 in MG-63 Cells
2.4. miR-126 Suppresses Cell Progression by Targeting Sox2
3. Discussion
4. Materials and Methods
4.1. Patients and Tissue Specimens
4.2. Cell Lines and Cell Culture
4.3. RNA Extraction, Reverse Transcription and Quantitative Real-Time PCR
4.4. Cell Transfection
4.5. Cell Proliferation Assay
4.6. Cell Apoptosis Analysis
4.7. Cell Migration and Invasion Assays
4.8. Plasmid Construction
4.9. Luciferase Assays
4.10. Western Blot Analysis
4.11. Statistical Analysis
5. Conclusions
Acknowledgments
Conflicts of Interest
References
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Yang, C.; Hou, C.; Zhang, H.; Wang, D.; Ma, Y.; Zhang, Y.; Xu, X.; Bi, Z.; Geng, S. RETRACTED: miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2. Int. J. Mol. Sci. 2014, 15, 423-437. https://doi.org/10.3390/ijms15010423
Yang C, Hou C, Zhang H, Wang D, Ma Y, Zhang Y, Xu X, Bi Z, Geng S. RETRACTED: miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2. International Journal of Molecular Sciences. 2014; 15(1):423-437. https://doi.org/10.3390/ijms15010423
Chicago/Turabian StyleYang, Chenglin, Chunying Hou, Hepeng Zhang, Dewei Wang, Yan Ma, Yunqi Zhang, Xiaoyan Xu, Zhenggang Bi, and Shuo Geng. 2014. "RETRACTED: miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2" International Journal of Molecular Sciences 15, no. 1: 423-437. https://doi.org/10.3390/ijms15010423