Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom
Abstract
:1. Introduction
2. Results
2.1. Western Blotting (WB) and Real Time-Polymerase Chain Reaction (qPCR)
2.2. Immunohistochemistry (IHC)
2.3. AQP4
2.4. Cav-1
3. Discussion
3.1. AQP4
3.2. Cav-1
4. Materials and Methods
4.1. Venom and Animals
4.2. Envenoming Procedure
4.3. IHC
IHC Analysis
4.4. qPCR
4.5. Western Blotting (WB)
4.6. Statistical Analysis
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Soares, E.S.; Stávale, L.M.; Mendonça, M.C.P.; Coope, A.; Cruz-Höfling, M.A.d. Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom. Int. J. Mol. Sci. 2016, 17, 1462. https://doi.org/10.3390/ijms17111462
Soares ES, Stávale LM, Mendonça MCP, Coope A, Cruz-Höfling MAd. Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom. International Journal of Molecular Sciences. 2016; 17(11):1462. https://doi.org/10.3390/ijms17111462
Chicago/Turabian StyleSoares, Edilene S., Leila M. Stávale, Monique C. P. Mendonça, Andressa Coope, and Maria Alice da Cruz-Höfling. 2016. "Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom" International Journal of Molecular Sciences 17, no. 11: 1462. https://doi.org/10.3390/ijms17111462