The Human Ovary and Future of Fertility Assessment in the Post-Genome Era
Abstract
:1. Introduction
2. Proteomics for Selection of Competent Embryos and Oocytes in IVF
2.1. Follicular Fluid: An Inexhaustible Biosource for Investigation of Competence Biomarkers
2.1.1. Role of Inflammation and Coagulation Cascades in IVF
2.1.2. Impact of Extracellular Matrix Turnover on Oocyte Quality
2.1.3. Involvement of Lipid Metabolism in the Success of IVF
2.2. A New Way of Predicting IVF Success: The Cumulus–Oocyte Complex
3. Ensuring Normal Pregnancy in Patients with Polycystic Ovary Syndrome through Proteomics
4. The Future of Human Ovary Proteomics
4.1. In Vivo Mass Spectrometry
4.2. Proteomics to Help Engineer a Transplantable Artificial Ovary
4.3. Challenges of Proteomic Studies of the Human Ovary
4.4. Proteomics Is Not an Island: The Added Value of Proteogenomics
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Ouni, E.; Vertommen, D.; Amorim, C.A. The Human Ovary and Future of Fertility Assessment in the Post-Genome Era. Int. J. Mol. Sci. 2019, 20, 4209. https://doi.org/10.3390/ijms20174209
Ouni E, Vertommen D, Amorim CA. The Human Ovary and Future of Fertility Assessment in the Post-Genome Era. International Journal of Molecular Sciences. 2019; 20(17):4209. https://doi.org/10.3390/ijms20174209
Chicago/Turabian StyleOuni, Emna, Didier Vertommen, and Christiani A. Amorim. 2019. "The Human Ovary and Future of Fertility Assessment in the Post-Genome Era" International Journal of Molecular Sciences 20, no. 17: 4209. https://doi.org/10.3390/ijms20174209