Ultrafast Processes Occurring in Radiolysis of Highly Concentrated Solutions of Nucleosides/Tides
Abstract
:1. Introduction
1.1. Ultrafast Processes in Water Radiolysis
1.2. Effect of Radiation in Concentrated Solutions
1.3. Studies of Biomolecule Model Systems
2. Ultrafast Hole and Electron Transfer under Irradiation
2.1. Elucidation of Pathways of Hole Transfer Processes Employing Concentrated Nucleotide Solutions
2.1.1. Backbone-to-Base Hole Transfer
2.1.2. Base-to-Backbone and Phosphate-to-Sugar Hole Transfer Process
2.2. Excess Electron-Mediated Bond Dissociation in Bulk Solutions
2.2.1. Can Prehydrated Electrons (epre−) Cause Bond Breakage Via DEA?
2.2.2. Picosecond Pulse Radiolysis Measurement of the Initial Yield of Formation of esol‒ in a Solution Leads to Study the Reaction of epre‒ with Solute
2.2.3. Reactivity of epre‒ with Nucleobases (X), Nucleosides, and 5′-Nucleotides (XMP) in Water
2.2.4. The Reactivity of Quasi-Free Electrons Towards Nucleoside in DEG
3. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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DNA Bases | k (H2PO4•) L mol−1s−1 | E0/V (dB•+/dB) |
---|---|---|
G | 6.9 × 108 | 1.47 |
A | 2.4 × 108 | 1.94 |
T | 1.1 × 109 | 2.09 |
C | <5 × 107 | 2.12 |
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MA, J.; Denisov, S.A.; Adhikary, A.; Mostafavi, M. Ultrafast Processes Occurring in Radiolysis of Highly Concentrated Solutions of Nucleosides/Tides. Int. J. Mol. Sci. 2019, 20, 4963. https://doi.org/10.3390/ijms20194963
MA J, Denisov SA, Adhikary A, Mostafavi M. Ultrafast Processes Occurring in Radiolysis of Highly Concentrated Solutions of Nucleosides/Tides. International Journal of Molecular Sciences. 2019; 20(19):4963. https://doi.org/10.3390/ijms20194963
Chicago/Turabian StyleMA, Jun, Sergey A. Denisov, Amitava Adhikary, and Mehran Mostafavi. 2019. "Ultrafast Processes Occurring in Radiolysis of Highly Concentrated Solutions of Nucleosides/Tides" International Journal of Molecular Sciences 20, no. 19: 4963. https://doi.org/10.3390/ijms20194963