Next Article in Journal
Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury
Next Article in Special Issue
Targeting the PD-1/PD-L1 Pathway in Renal Cell Carcinoma
Previous Article in Journal
Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice
Previous Article in Special Issue
PD-L1 Expression in Systemic Immune Cell Populations as a Potential Predictive Biomarker of Responses to PD-L1/PD-1 Blockade Therapy in Lung Cancer
 
 
Review
Peer-Review Record

Glial Cell Expression of PD-L1

Int. J. Mol. Sci. 2019, 20(7), 1677; https://doi.org/10.3390/ijms20071677
by Priyanka Chauhan and James R. Lokensgard *
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2019, 20(7), 1677; https://doi.org/10.3390/ijms20071677
Submission received: 27 February 2019 / Revised: 27 March 2019 / Accepted: 2 April 2019 / Published: 4 April 2019
(This article belongs to the Special Issue PD-L1, A Master Regulator of Immunity)

Round  1

Reviewer 1 Report

The manuscript is really interesting, well written and structured. it is acceptable for publication

Author Response

Reviewer #1 did not request revisions. 

Reviewer 2 Report

For a neuro-oncologist the authors provide an unusual insight into immune mechanisms of the brain that might be very necessary at this time. Blocking PD1:PDL1 signaling in brain could also enhance antiviral activity in the brain.

The authors should clarify at the begin that they essentially review data from mouse models and put a special emphasis when they refer about human data

Author Response

“…clarify at the begin that they essentially review data from mouse models and put a special emphasis when they refer about human data.”

In response to Reviewer #2, we have added a sentence on page 4 (line 40) stating that we primarily discuss data derived from murine models and specifically indicate if the study was carried out using human cells or samples, as discussed on page 5 (line 3).

Back to TopTop