Glial Cell Expression of PD-L1
Round 1
Reviewer 1 Report
The manuscript is really interesting, well written and structured. it is acceptable for publication
Author Response
Reviewer #1 did not request revisions.
Reviewer 2 Report
For a neuro-oncologist the authors provide an unusual insight into immune mechanisms of the brain that might be very necessary at this time. Blocking PD1:PDL1 signaling in brain could also enhance antiviral activity in the brain.
The authors should clarify at the begin that they essentially review data from mouse models and put a special emphasis when they refer about human data
Author Response
“…clarify at the begin that they essentially review data from mouse models and put a special emphasis when they refer about human data.”
In response to Reviewer #2, we have added a sentence on page 4 (line 40) stating that we primarily discuss data derived from murine models and specifically indicate if the study was carried out using human cells or samples, as discussed on page 5 (line 3).