Continuum Models of Membrane Fusion: Evolution of the Theory
Abstract
:1. Introduction
2. Results
2.1. Approaches to a Description of Membrane Fusion
2.2. Classical Fusion Model: Stalk, Hemifusion Diaphragm, Fusion Pore
2.3. Evolution of Elastic Models
2.4. Hydration and Hydrophobic Interactions of Membranes
2.5. Mechanisms of Fusion Protein Functioning
2.6. Continuous Fusion Pathway: From Two Parallel Membranes to Stalk
2.7. The Continuous Trajectory of the Fusion: From Stalk to Fusion Pore
2.8. Molecular Modeling of the Fusion Process. Non-Classical Intermediates
2.9. Leaky Fusion: Experimental Observations and Continuum Modeling
3. Conclusions
Funding
Conflicts of Interest
References
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Akimov, S.A.; Molotkovsky, R.J.; Kuzmin, P.I.; Galimzyanov, T.R.; Batishchev, O.V. Continuum Models of Membrane Fusion: Evolution of the Theory. Int. J. Mol. Sci. 2020, 21, 3875. https://doi.org/10.3390/ijms21113875
Akimov SA, Molotkovsky RJ, Kuzmin PI, Galimzyanov TR, Batishchev OV. Continuum Models of Membrane Fusion: Evolution of the Theory. International Journal of Molecular Sciences. 2020; 21(11):3875. https://doi.org/10.3390/ijms21113875
Chicago/Turabian StyleAkimov, Sergey A., Rodion J. Molotkovsky, Peter I. Kuzmin, Timur R. Galimzyanov, and Oleg V. Batishchev. 2020. "Continuum Models of Membrane Fusion: Evolution of the Theory" International Journal of Molecular Sciences 21, no. 11: 3875. https://doi.org/10.3390/ijms21113875