Lens Connexin Channels Show Differential Permeability to Signaling Molecules
Abstract
:1. Introduction
2. Lens Connexin Permeability
2.1. Cx50 Has Significantly Reduced Permeability to cAMP Compared to Cx43 and Cx46
2.2. Cx50 Has Greatly Reduced Permeability to IP3 Compared to CX43
2.3. Cx50 Has High Permeability to Ca2+
2.4. Summary of Large Solute Permeability between Cx43, Cx46, and Cx50
3. Future Directions
Funding
Conflicts of Interest
Abbreviations
Cx | connexin |
cAMP | 3′,5′-cyclic adenosine monophosphate |
IP3 | inositol 1,4,5-trisphosphate |
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Brink, P.R.; Valiunas, V.; White, T.W. Lens Connexin Channels Show Differential Permeability to Signaling Molecules. Int. J. Mol. Sci. 2020, 21, 6943. https://doi.org/10.3390/ijms21186943
Brink PR, Valiunas V, White TW. Lens Connexin Channels Show Differential Permeability to Signaling Molecules. International Journal of Molecular Sciences. 2020; 21(18):6943. https://doi.org/10.3390/ijms21186943
Chicago/Turabian StyleBrink, Peter R., Virginijus Valiunas, and Thomas W. White. 2020. "Lens Connexin Channels Show Differential Permeability to Signaling Molecules" International Journal of Molecular Sciences 21, no. 18: 6943. https://doi.org/10.3390/ijms21186943