The Gut Barrier, Intestinal Microbiota, and Liver Disease: Molecular Mechanisms and Strategies to Manage
Abstract
:1. Introduction
2. Intestinal Barrier Function and Microbiota
3. Leaky Gut, Gut Microbiota Relationship and Liver Disease
3.1. Animal Studies
3.2. Human Studies
4. Current Main Strategies to Treat Liver Disease
4.1. Drug Therapies
4.2. Diet, Liver Disease and Gut Permeability
4.3. Probiotics Administration As a Strategy for Liver Disease Treatment
4.4. Physical Exercise and Liver Disease
Exercise on Gut Barrier Permeability and Microbiome
5. Further Directions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Plaza-Díaz, J.; Solís-Urra, P.; Rodríguez-Rodríguez, F.; Olivares-Arancibia, J.; Navarro-Oliveros, M.; Abadía-Molina, F.; Álvarez-Mercado, A.I. The Gut Barrier, Intestinal Microbiota, and Liver Disease: Molecular Mechanisms and Strategies to Manage. Int. J. Mol. Sci. 2020, 21, 8351. https://doi.org/10.3390/ijms21218351
Plaza-Díaz J, Solís-Urra P, Rodríguez-Rodríguez F, Olivares-Arancibia J, Navarro-Oliveros M, Abadía-Molina F, Álvarez-Mercado AI. The Gut Barrier, Intestinal Microbiota, and Liver Disease: Molecular Mechanisms and Strategies to Manage. International Journal of Molecular Sciences. 2020; 21(21):8351. https://doi.org/10.3390/ijms21218351
Chicago/Turabian StylePlaza-Díaz, Julio, Patricio Solís-Urra, Fernando Rodríguez-Rodríguez, Jorge Olivares-Arancibia, Miguel Navarro-Oliveros, Francisco Abadía-Molina, and Ana I. Álvarez-Mercado. 2020. "The Gut Barrier, Intestinal Microbiota, and Liver Disease: Molecular Mechanisms and Strategies to Manage" International Journal of Molecular Sciences 21, no. 21: 8351. https://doi.org/10.3390/ijms21218351