Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies
Abstract
:1. Introduction
2. Cellular Heterogeneity of Bone Marrow Stroma Cells
3. Effects of BMSCs on Malignant B Cells
3.1. BMSCs and Apoptosis
3.2. BMSCs and Oncogenes
3.3. BMSCs and Metabolism
4. Reciprocal Effects On BMSCs
4.1. Cell Adhesion Mediated Remodelling of Stroma Cells
4.2. Soluble Determinants of Stroma Remodelling
4.3. Activated Signalling Pathways in Remodelled BMSCs
4.4. Metabolic Remodelling of BMSCs
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Mangolini, M.; Ringshausen, I. Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies. Int. J. Mol. Sci. 2020, 21, 1466. https://doi.org/10.3390/ijms21041466
Mangolini M, Ringshausen I. Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies. International Journal of Molecular Sciences. 2020; 21(4):1466. https://doi.org/10.3390/ijms21041466
Chicago/Turabian StyleMangolini, Maurizio, and Ingo Ringshausen. 2020. "Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies" International Journal of Molecular Sciences 21, no. 4: 1466. https://doi.org/10.3390/ijms21041466