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Article
Peer-Review Record

CD85k Contributes to Regulatory T Cell Function in Chronic Viral Infections

Int. J. Mol. Sci. 2021, 22(1), 31; https://doi.org/10.3390/ijms22010031
by Anna Estrada Brull 1,†, Felix Rost 1,†, Josua Oderbolz 2, Florian R. Kirchner 1,3, Salomé Leibundgut-Landmann 1,3, Annette Oxenius 2 and Nicole Joller 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2021, 22(1), 31; https://doi.org/10.3390/ijms22010031
Submission received: 14 December 2020 / Revised: 16 December 2020 / Accepted: 17 December 2020 / Published: 22 December 2020
(This article belongs to the Special Issue Recent Advances in T Cell Immunity)

Round 1

Reviewer 1 Report

The authors definitely improved their manuscript during revision and tried to include all suggestions and additions of the reviewers in the manuscript. In more detail, the analysis of another time point highlights the role of CD85k and ALCAM in the latency of mCMV. I only have one suggestion prior publication, the newly added reference 43 does not fit as reference for MCK-2 repair mCMV, here MCMV-Dm157 was used but not generated and therefore Jordan et al. JVI 2011 was correctly cited.

As far as mentioned by the Brull and colleagues they use a mCMV.WT on MCK2repair background. Also for this virus Jordan et al.  JVI 2011 should be cited.

 

Jordan, S., Krause, J., Prager, A., Mitrovic, M., Jonjic, S., Koszinowski, U.H., and Adler, B. (2011). Virus progeny of murine cytomegalovirus bacterial artifi- cial chromosome pSM3fr show reduced growth in salivary Glands due to a fixed mutation of MCK-2. J. Virol. 85, 10346–10353

Author Response

We thank the reviewer for spotting this mistake and have replaced the reference with the correct one.

Reviewer 2 Report

No further comments from this reviewer.

Author Response

Thank you for the positive feedback.

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