Function of Circular RNAs in Fish and Their Potential Application as Biomarkers
Abstract
:1. Introduction
2. Bioinformatic Analysis of circRNAs
3. Role of circRNAs in Myogenesis and Growth
4. CircRNAs as Regulators of the Immune System
5. Advancements in Teleost circRNA Research
6. Potential Application of circRNAs in Aquaculture
7. Major Challenges of circRNA Research in Aquaculture
8. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Species | Common Name | Tissue/Cell Type | RNA Treatment | Detected circRNAs | Validated circRNAs | Reference |
---|---|---|---|---|---|---|
Bos taurus | Cattle | Skeletal muscle | RNase R+ rRNA− | 12,981 | 17 | [74] |
Capra aegagrus hircus | Wild goat | Skeletal muscle | RNase R+ rRNA− | 9090 | 4 | [75] |
Gallus gallus | Chicken | Skeletal muscle | RNase R+ rRNA− | 13,377 | 8 | [76] |
Homo sapiens | Human | C2C12 myoblasts | rRNA− | 2175 | 31 | [77] |
Macaca mulatta | Rhesus monkey | Primary myoblasts | RNase R | 2100 | 29 | [78] |
Mus musculus | House mouse | C2C12 myoblasts | RNase R+ rRNA− | 37,751 | 10 | [79] |
C2C12 myoblasts | rRNA− | 1592 | 31 | [77] | ||
Oreochromis niloticus | Nile tilapia | Skeletal muscle | rRNA− | 622 | - | [57] |
Ovis aries | Sheep | Skeletal muscle | RNase R+ | 6000 | 10 | [80] |
Sus scrofa | Pig | Skeletal muscle | rRNA− | 4402 | 2 | [81] |
Skeletal muscle | RNase R+ rRNA− | 7968 | 6 | [82] |
CircRNA | Species | Tissue/Cell | Biological Role | Mode of Action | Reference |
---|---|---|---|---|---|
Circ-ZNF609 | Homo sapiens | C2C12 | Myoblast proliferation | Protein encoding | [77] |
CircTTN | Bos taurus | Skeletal muscle | miRNA sponge | [91] | |
CircINSR | Bos taurus | Skeletal muscle | miRNA sponge | [86] | |
CircFUT10 | Bos taurus | Skeletal muscle | miRNA sponge | [87] | |
CircSVIL | Gallus gallus | Skeletal muscle | miRNA sponge | [89] | |
CircFGFR2 | Gallus gallus | DF-1 | miRNA sponge | [92] | |
CircRBFOX2 | Gallus gallus | Skeletal muscle | miRNA sponge | [88] | |
CircSNX29 | Bos taurus | Skeletal muscle | Myoblast differentiation | miRNA sponge | [93] |
CircHUWE1 | Bos taurus | Skeletal muscle | [94] | ||
CircLMO7 | Bos taurus | Skeletal muscle | [74] | ||
CircHIPK3 | Gallus gallus | Skeletal muscle | [95] |
Species | Common Name | Infection Type | Tissue | DE * circRNAs | Reference |
---|---|---|---|---|---|
Ctenopharyngodon idellus | Grass carp | Viral | Spleen | 41 | [113] |
Kidney | 76 | [114] | |||
Kidney | - | [115] | |||
Oreochromis niloticus | Nile tilapia | Bacterial | Brain | 837 | [116] |
Paralichthys olivaceus | Japanese flounder | Bacterial | Intestine | 62 | [117] |
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Rbbani, G.; Nedoluzhko, A.; Galindo-Villegas, J.; Fernandes, J.M.O. Function of Circular RNAs in Fish and Their Potential Application as Biomarkers. Int. J. Mol. Sci. 2021, 22, 7119. https://doi.org/10.3390/ijms22137119
Rbbani G, Nedoluzhko A, Galindo-Villegas J, Fernandes JMO. Function of Circular RNAs in Fish and Their Potential Application as Biomarkers. International Journal of Molecular Sciences. 2021; 22(13):7119. https://doi.org/10.3390/ijms22137119
Chicago/Turabian StyleRbbani, Golam, Artem Nedoluzhko, Jorge Galindo-Villegas, and Jorge M. O. Fernandes. 2021. "Function of Circular RNAs in Fish and Their Potential Application as Biomarkers" International Journal of Molecular Sciences 22, no. 13: 7119. https://doi.org/10.3390/ijms22137119