Expression of Lymphatic Markers in the Berger’s Space and Bursa Premacularis
Abstract
:1. Introduction
2. Results
2.1. Anatomical Similarities between the BS and the BPM Observed during Specimen Collection
2.2. Immunostaining of the BPM and the Vitreous Core (VC) with Antibodies for Fibrillin-1 and -2
2.3. Immunostaining of the BS, BPM, and VC with Antibodies for Fibrillin-1 and -2, Podoplanin, and LYVE-1
3. Discussion
4. Materials and Methods
4.1. Collection of the BS, BPM, and VC Specimens
4.2. Immunostaining of the BPM and VC with Antibodies for Fibrillin-1 and -2
4.3. Immunostaining of the BS, BPM, and VC Specimens with Antibodies for Fibrillin-1 and -2, Podoplanin, and LYVE-1
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
BPM | bursa premacularis |
PVD | posterior vitreous detachment |
LYVE-1 | lymphatic vessel endothelial hyaluronan receptor 1 |
BS | Berger’s space |
AHM | anterior hyaloid membrane |
TA | triamcinolone acetonide |
VC | vitreous core |
SS-OCT | swept-source optical coherence tomography |
ERM | epiretinal membrane |
MH | macular hole |
PDR | proliferative diabetic retinopathy |
3D-OCT | three-dimensional optical coherence tomography |
ABA | Agaricus bisporus agglutinin |
AQP4 | aquaporin-4 |
SD-OCT | spectral domain optical coherence tomography |
YAG | yttrium aluminum garnet |
IOP | intraocular pressure |
RPE | retinal pigment epithelial |
GFAP | glial fibrillary acidic protein |
CME | cystoid macular edema |
PBS | phosphate buffered saline |
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Morishita, S.; Sato, T.; Oosuka, S.; Horie, T.; Kida, T.; Oku, H.; Nakamura, K.; Takai, S.; Jin, D.; Ikeda, T. Expression of Lymphatic Markers in the Berger’s Space and Bursa Premacularis. Int. J. Mol. Sci. 2021, 22, 2086. https://doi.org/10.3390/ijms22042086
Morishita S, Sato T, Oosuka S, Horie T, Kida T, Oku H, Nakamura K, Takai S, Jin D, Ikeda T. Expression of Lymphatic Markers in the Berger’s Space and Bursa Premacularis. International Journal of Molecular Sciences. 2021; 22(4):2086. https://doi.org/10.3390/ijms22042086
Chicago/Turabian StyleMorishita, Seita, Takaki Sato, Shou Oosuka, Taeko Horie, Teruyo Kida, Hidehiro Oku, Kimitoshi Nakamura, Shinji Takai, Denan Jin, and Tsunehiko Ikeda. 2021. "Expression of Lymphatic Markers in the Berger’s Space and Bursa Premacularis" International Journal of Molecular Sciences 22, no. 4: 2086. https://doi.org/10.3390/ijms22042086