The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases
Abstract
:1. Zebrafish as a Model for Biomedical Research
1.1. General Features of Zebrafish
1.2. Advantages of Using Zebrafish as an Experimental Model
1.3. Circadian Rhythms in Zebrafish
2. Melatonin in Zebrafish
2.1. Synthesis and Metabolism of Melatonin
2.2. Mechanisms of Action of Melatonin
2.3. Pineal Melatonin Properties
2.4. Extrapineal Melatonin Properties
3. Therapeutic Properties of Melatonin in Zebrafish Models of Disease
3.1. Melatonin in Parkinsonian Zebrafish
3.2. Melatonin against Epilepsy in Zebrafish
3.3. Protective Effects of Melatonin against Cardiovascular Damage in Zebrafish
3.4. Melatonin and Obesity in Zebrafish
3.5. Regulation of Bone Metabolism by Melatonin in Zebrafish
3.6. Melatonin in Zebrafish Model of Psychiatric Diseases
3.7. Melatonin, Aging, and Chronodisruption in Zebrafish
4. Prospective Research
5. Concluding Remarks—Importance to Humans
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Aranda-Martínez, P.; Fernández-Martínez, J.; Ramírez-Casas, Y.; Guerra-Librero, A.; Rodríguez-Santana, C.; Escames, G.; Acuña-Castroviejo, D. The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases. Int. J. Mol. Sci. 2022, 23, 7438. https://doi.org/10.3390/ijms23137438
Aranda-Martínez P, Fernández-Martínez J, Ramírez-Casas Y, Guerra-Librero A, Rodríguez-Santana C, Escames G, Acuña-Castroviejo D. The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases. International Journal of Molecular Sciences. 2022; 23(13):7438. https://doi.org/10.3390/ijms23137438
Chicago/Turabian StyleAranda-Martínez, Paula, José Fernández-Martínez, Yolanda Ramírez-Casas, Ana Guerra-Librero, César Rodríguez-Santana, Germaine Escames, and Darío Acuña-Castroviejo. 2022. "The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases" International Journal of Molecular Sciences 23, no. 13: 7438. https://doi.org/10.3390/ijms23137438