Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities
Abstract
:1. Introduction
2. Overview of COMP
3. COMP and Skeleton Diseases
3.1. COMP and Cartilage Homeostasis
3.2. COMP Mutations and Skeleton Diseases
3.3. The Use of COMP as a Biomarker for OA, RA, and Other Skeleton Diseases
3.4. Treatments and Targeting COMP in OA and Other Pathologies
4. COMP and Cancer/Cancer Malignancy/Cancer Progression
4.1. Hepatocellular Carcinoma
4.2. Colon Cancer
4.3. Breast Cancer
4.4. Others
5. COMP and Cardiovascular Disease
6. COMP and Fibrosis
7. COMP and Other Diseases
8. Conclusions and Perspective
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Cui, J.; Zhang, J. Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities. Int. J. Mol. Sci. 2022, 23, 9253. https://doi.org/10.3390/ijms23169253
Cui J, Zhang J. Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities. International Journal of Molecular Sciences. 2022; 23(16):9253. https://doi.org/10.3390/ijms23169253
Chicago/Turabian StyleCui, Jiarui, and Jiaming Zhang. 2022. "Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities" International Journal of Molecular Sciences 23, no. 16: 9253. https://doi.org/10.3390/ijms23169253