Genome of Laudakia sacra Provides New Insights into High-Altitude Adaptation of Ectotherms
Abstract
:1. Introduction
2. Results
2.1. De Novo Assembly of L. sacra Genome
2.2. Phylogenetic Reconstruction
2.3. Positively Selected Genes (PSGs) and Quickly Evolving Genes (QEGs) Analyses
2.4. Potential Genetic Basis of Adaptation to Plateau Environments
3. Discussion
3.1. Adaptation to Hypoxia
3.2. Adaptation to UV Radiation
3.3. Adaptation to Cold
4. Materials and Methods
4.1. Genome Sequencing and Assembly
4.2. Gene Structural and Functional Annotations
4.3. Phylogenetic Tree Construction and Divergence Time Estimation
4.4. Gene Family Expansion and Contraction
4.5. Common Quickly Evolving Genes (CQEGs) in Plateau Animals
4.6. Positively Selected Genes (PSGs) and Quickly Evolving Genes (QEGs) in L. sacra Genome
4.7. Species-Specific Mutations and Alignment Visualization
4.8. Chromosome Synteny with S. undulatus
4.9. Enrichment Analysis and Structural Prediction
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Yan, C.; Zhang, Z.-Y.; Lv, Y.; Wang, Z.; Jiang, K.; Li, J.-T. Genome of Laudakia sacra Provides New Insights into High-Altitude Adaptation of Ectotherms. Int. J. Mol. Sci. 2022, 23, 10081. https://doi.org/10.3390/ijms231710081
Yan C, Zhang Z-Y, Lv Y, Wang Z, Jiang K, Li J-T. Genome of Laudakia sacra Provides New Insights into High-Altitude Adaptation of Ectotherms. International Journal of Molecular Sciences. 2022; 23(17):10081. https://doi.org/10.3390/ijms231710081
Chicago/Turabian StyleYan, Chaochao, Zhi-Yi Zhang, Yunyun Lv, Zeng Wang, Ke Jiang, and Jia-Tang Li. 2022. "Genome of Laudakia sacra Provides New Insights into High-Altitude Adaptation of Ectotherms" International Journal of Molecular Sciences 23, no. 17: 10081. https://doi.org/10.3390/ijms231710081