Roles of Antimicrobial Peptides in Gynecological Cancers

Round 1

Reviewer 1 Report

The review by Chongyi Zhao et al., “Roles of antimicrobial peptides in gynecological cancers” is a short, clear, briefly exposed study and deserves to be published.

Some minor points:

- Page 2, line 50-52: Some details on the statistics and predictions for 2040 should be added, like population involved, predictions consider the vaccines or not, etc.

- Roles and implications of AMPs during pregnancy are not mentioned and a short section about this would improve the quality of the review.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

The manuscript is a review of the literature summarizing the current understanding of the roles of antimicrobial peptides in the development of female reproductive tract tumors. The authors emphasize that AMPs play a dual role in the development of gynecological cancers, on the one hand, inhibiting the oncological transformation of cells, and on the other hand, they have a stimulating effect on the formation of tumors. The authors present a critical analysis of the literature on these issues, which allows to evaluate the main potential areas of use of AMP in the diagnosis, prediction of the outcome and therapy of these diseases.

I suppose that the review is well written, requires no further elaboration and can be published in the form presented.

Author Response

Thank you very much for your encouraging comment.