Early Life Stress Affects Bdnf Regulation: A Role for Exercise Interventions
, Christina M. Nelson 2 and Tania L. Roth 1
Round 1
Reviewer 1 Report
The review entitled “Early life stress affects neurotrophin regulation: A role for exercise interventions” by Campbell et al. is interesting, comprehensive, and well written. I suggest only a few minor revisions:
Fig. 1. The legend should explain some points, such as the meaning of color shades and different colored points in the time scale.
Table 2. In the title, funding should be replaced by findings
Reference 27. The citation format has to be revised.
Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
The paper by Dr Campbell et al., entitled "Early life stress affects neurotrophin regulation: A role for exercise interventions", is an interesting review dealing with the deleterious effects of early life stress (ELS) on brain development, with a focus on the ELS-induced alterations in neurotrophin expression during the early life.
The review is well organized and it addresses the main focus with clarity and appropriate references. My only suggestion is to re-title the review, since it does not address the effects of ELS on all neurotrophins but BDNF. Abstract should be re-written accordingly.
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
