The Role of Type VI Collagen in Alveolar Bone
Abstract
:1. Introduction
2. Results
2.1. Type VI Collagen Is Expressed in Oral Tissues
2.2. Col6α2-KO Mice Have Compromised Oral Tissues
2.3. Type VI Collagen Affects ECM Molecules in the Alveolar Bone
2.4. Col6α2-KO Mice Have More Bone Resorption in an Induced Model of Periodontitis Compared with WT
3. Discussion
4. Materials and Methods
4.1. Animal Experiments
4.2. Micro-Computed Tomography (µCT)
4.3. Immunohistochemistry
4.4. Protein Extraction
4.5. Proteomics
4.6. Ligature-Induced Periodontitis Model
4.7. Statistics
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Komori, T.; Pham, H.; Jani, P.; Perry, S.; Wang, Y.; Kilts, T.M.; Li, L.; Young, M.F. The Role of Type VI Collagen in Alveolar Bone. Int. J. Mol. Sci. 2022, 23, 14347. https://doi.org/10.3390/ijms232214347
Komori T, Pham H, Jani P, Perry S, Wang Y, Kilts TM, Li L, Young MF. The Role of Type VI Collagen in Alveolar Bone. International Journal of Molecular Sciences. 2022; 23(22):14347. https://doi.org/10.3390/ijms232214347
Chicago/Turabian StyleKomori, Taishi, Hai Pham, Priyam Jani, Sienna Perry, Yan Wang, Tina M. Kilts, Li Li, and Marian F. Young. 2022. "The Role of Type VI Collagen in Alveolar Bone" International Journal of Molecular Sciences 23, no. 22: 14347. https://doi.org/10.3390/ijms232214347