Insight into the Molecular Basis Underlying Chromothripsis
Abstract
:1. Introduction
2. Chromothripsis (cth)
2.1. Mechanisms Underlying the Chromothripsis Process
2.2. Prevalence of Chromothripsis
3. Chromothripsis in Haematological Malignancies
3.1. Multiple Myeloma (MM)
3.2. Chronic Lymphocytic Leukaemia (CLL)
3.3. Acute Myeloid Leukaemia (AML)
3.4. Acute Lymphoblastic Leukaemia (ALL)
3.5. Chromothripsis-like Events in Congenital Disorders
4. Diagnostics of Chromothripsis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Ostapińska, K.; Styka, B.; Lejman, M. Insight into the Molecular Basis Underlying Chromothripsis. Int. J. Mol. Sci. 2022, 23, 3318. https://doi.org/10.3390/ijms23063318
Ostapińska K, Styka B, Lejman M. Insight into the Molecular Basis Underlying Chromothripsis. International Journal of Molecular Sciences. 2022; 23(6):3318. https://doi.org/10.3390/ijms23063318
Chicago/Turabian StyleOstapińska, Katarzyna, Borys Styka, and Monika Lejman. 2022. "Insight into the Molecular Basis Underlying Chromothripsis" International Journal of Molecular Sciences 23, no. 6: 3318. https://doi.org/10.3390/ijms23063318