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Review

Applications of Plasma-Activated Water in Dentistry: A Review

by
Noala Vicensoto Moreira Milhan
1,*,
William Chiappim
2,
Aline da Graça Sampaio
1,
Mariana Raquel da Cruz Vegian
1,
Rodrigo Sávio Pessoa
2 and
Cristiane Yumi Koga-Ito
1,3
1
Oral Biopathology Graduate Program, São José dos Campos Institute of Science & Technology, São Paulo State University, UNESP, São Paulo 12245-000, Brazil
2
Plasma and Processes Laboratory, Department of Physics, Aeronautics Institute of Technology, Praça Marechal Eduardo Gomes 50, São José dos Campos 12228-900, Brazil
3
Department of Environment Engineering, São José dos Campos Institute of Science & Technology, São Paulo State University, UNESP, São Paulo 12247-016, Brazil
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(8), 4131; https://doi.org/10.3390/ijms23084131
Submission received: 5 March 2022 / Revised: 5 April 2022 / Accepted: 6 April 2022 / Published: 8 April 2022
(This article belongs to the Special Issue Dental Biomaterials: From Fundamental Principles to Clinical Applications)
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Abstract

The activation of water by non-thermal plasma creates a liquid with active constituents referred to as plasma-activated water (PAW). Due to its active constituents, PAW may play an important role in different fields, such as agriculture, the food industry and healthcare. Plasma liquid technology has received attention in recent years due to its versatility and good potential, mainly focused on different health care purposes. This interest has extended to dentistry, since the use of a plasma–liquid technology could bring clinical advantages, compared to direct application of non-thermal atmospheric pressure plasmas (NTAPPs). The aim of this paper is to discuss the applicability of PAW in different areas of dentistry, according to the published literature about NTAPPs and plasma–liquid technology. The direct and indirect application of NTAPPs are presented in the introduction. Posteriorly, the main reactors for generating PAW and its active constituents with a role in biomedical applications are specified, followed by a section that discusses, in detail, the use of PAW as a tool for different oral diseases.
Keywords: plasma-activated water; plasma-treated water; atmospheric plasma; gliding arc discharge; DBD; dentistry; decontamination; oral cancer; tooth bleaching plasma-activated water; plasma-treated water; atmospheric plasma; gliding arc discharge; DBD; dentistry; decontamination; oral cancer; tooth bleaching

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MDPI and ACS Style

Milhan, N.V.M.; Chiappim, W.; Sampaio, A.d.G.; Vegian, M.R.d.C.; Pessoa, R.S.; Koga-Ito, C.Y. Applications of Plasma-Activated Water in Dentistry: A Review. Int. J. Mol. Sci. 2022, 23, 4131. https://doi.org/10.3390/ijms23084131

AMA Style

Milhan NVM, Chiappim W, Sampaio AdG, Vegian MRdC, Pessoa RS, Koga-Ito CY. Applications of Plasma-Activated Water in Dentistry: A Review. International Journal of Molecular Sciences. 2022; 23(8):4131. https://doi.org/10.3390/ijms23084131

Chicago/Turabian Style

Milhan, Noala Vicensoto Moreira, William Chiappim, Aline da Graça Sampaio, Mariana Raquel da Cruz Vegian, Rodrigo Sávio Pessoa, and Cristiane Yumi Koga-Ito. 2022. "Applications of Plasma-Activated Water in Dentistry: A Review" International Journal of Molecular Sciences 23, no. 8: 4131. https://doi.org/10.3390/ijms23084131

APA Style

Milhan, N. V. M., Chiappim, W., Sampaio, A. d. G., Vegian, M. R. d. C., Pessoa, R. S., & Koga-Ito, C. Y. (2022). Applications of Plasma-Activated Water in Dentistry: A Review. International Journal of Molecular Sciences, 23(8), 4131. https://doi.org/10.3390/ijms23084131

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