Tissue-Specific Regulation of CFTR Gene Expression
Abstract
:1. Introduction
2. Clinical Issues
3. Tissue Expression
4. Characteristics of the CFTR Locus
4.1. Promoter as a Housekeeping Gene
4.2. Cis-Regulation of the CFTR Gene
4.2.1. Airway
4.2.2. Intestine
4.2.3. Epididymis
4.2.4. Pancreas
4.3. Impact of CFTR Cis-Regulatory Variants?
4.4. microRNA and lncRNA
4.5. Modifier Genes
4.5.1. Pulmonary
4.5.2. Intestines
4.5.3. Epididymis
4.5.4. Pancreas
4.6. Complex Alleles
5. Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Blotas, C.; Férec, C.; Moisan, S. Tissue-Specific Regulation of CFTR Gene Expression. Int. J. Mol. Sci. 2023, 24, 10678. https://doi.org/10.3390/ijms241310678
Blotas C, Férec C, Moisan S. Tissue-Specific Regulation of CFTR Gene Expression. International Journal of Molecular Sciences. 2023; 24(13):10678. https://doi.org/10.3390/ijms241310678
Chicago/Turabian StyleBlotas, Clara, Claude Férec, and Stéphanie Moisan. 2023. "Tissue-Specific Regulation of CFTR Gene Expression" International Journal of Molecular Sciences 24, no. 13: 10678. https://doi.org/10.3390/ijms241310678