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Review
Peer-Review Record

Immunomodulation Therapies for Atherosclerosis: The Past, the Present, and the Future

Int. J. Mol. Sci. 2023, 24(13), 10979; https://doi.org/10.3390/ijms241310979
by Dalgisio Lecis 1,*, Gianluca Massaro 1, Daniela Benedetto 1, Marco Di Luozzo 1, Giulio Russo 1, Alessandro Mauriello 2, Massimo Federici 3 and Giuseppe Massimo Sangiorgi 1,4,*
Reviewer 1: Anonymous
Reviewer 2:
Int. J. Mol. Sci. 2023, 24(13), 10979; https://doi.org/10.3390/ijms241310979
Submission received: 28 May 2023 / Revised: 26 June 2023 / Accepted: 30 June 2023 / Published: 1 July 2023

Round 1

Reviewer 1 Report


Comments for author File: Comments.pdf


Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

In this review, the authors explored the experimental and clinical evidence supporting the use of immune-based therapies for atherosclerosis, with a particular focus on vaccination strategies. The aim of this review was to provide an overview of the past, present, and future of immunomodulation therapies for atherosclerosis.

 

Regarding concerns:

1.     The section 2 “Innate Immune Responses in Atherosclerosis” contains the phrase: “This section may be divided by subheadings.

Please explain your intention regarding this section.

 

2.      The authors should clarify the distinction between MDA-LDL and oxidized LDL. While MDA-LDL is a specific type of oxidized LDL, it is essential to differentiate between the two to avoid confusion in the reader. The authors could provide a more comprehensive explanation of oxidized LDL and its various forms to avoid misinterpretation.

3. There is no description for the figure 1.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

I have no further comments.

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