Next Article in Journal
A Benchmark Study of Protein–Fragment Complex Structure Calculations with NMR2
Previous Article in Journal
The Mechanotransduction Signaling Pathways in the Regulation of Osteogenesis
Previous Article in Special Issue
In-Depth Analysis of the N-Glycome of Colorectal Cancer Cell Lines
 
 
Article
Peer-Review Record

Reducing Sialylation Enhances Electrotaxis of Corneal Epithelial Cells

Int. J. Mol. Sci. 2023, 24(18), 14327; https://doi.org/10.3390/ijms241814327
by Bryan Le 1, Kan Zhu 1, Chelsea Brown 1, Brian Reid 1, Amin Cressman 2, Min Zhao 1,† and Fernando A. Fierro 2,*,†
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Int. J. Mol. Sci. 2023, 24(18), 14327; https://doi.org/10.3390/ijms241814327
Submission received: 25 August 2023 / Revised: 14 September 2023 / Accepted: 15 September 2023 / Published: 20 September 2023
(This article belongs to the Special Issue Glyco-Dynamics and Cell Signaling)

Round 1

Reviewer 1 Report

The manuscript by Le et al described modifying sialylated glycans strongly impacts the electrotaxis of corneal epithelial cells. The manuscript has been written well and the conclusions supported by data presented.

I recommend publication in current form.

 

Minor changes required.

Author Response

Thank you for reviewing our manuscript. 

Reviewer 2 Report

As attached

Comments for author File: Comments.pdf


Author Response

We are very thankful for the thorough review and have introduced all recommended changes.  

Reviewer 3 Report

Very good macuscript! The authors conducted rigorous research that has a potential to contribute to the literature. Article with proper scientific structure, coherent and well written. Clear aim of study, conclusions supported by the results. Although I recommend this article to the publication, some minor improvements could be made:

ln 52 - please add relevant citations

Figure D, Page 3; Figure C, Page 4 and Figure E on Page 6 - Very important figures for results understanding. It would be perfect, if authors could provide larger images. This could ensure better findings understanding. 

Ln 270-274 - Authors included conclusions in the discussion method. For true scientific purity, it would be beneficial if this fragment was removed and incoporated in the "Conclusions" section. 

Author Response

Thank you very much for the careful review. We introduced all suggested changes.

Back to TopTop