Prevalence of Congenital Color Vision Deficiency in Southern Taiwan and Detection of Female Carriers by Visual Pigment Gene Analysis
Abstract
:1. Introduction
2. Results
2.1. Part I: Survey of Color Vision of Students
2.2. Part II: Detection of Female Carriers
3. Discussion
4. Materials and Methods
4.1. Part I: Survey of the Color Vision of Students
4.2. Part II: Detection of Female Carriers
4.2.1. Color Vision Screening Tests
4.2.2. DNA Extraction
4.2.3. Long-Range and Secondary PCR (Two-Step)
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Ethics approval and consent to participate
References
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2019 | Age | Students No. of Total | % Of CVD in Male | % Of CVD in Female | % Of CVD in Total |
---|---|---|---|---|---|
Grade 1 | 7 | 22,681 | 3.07% | 0.12% | 1.63% |
Grade 4 | 11 | 18,494 | 3.41% | 0.09% | 1.80% |
Grade 7 | 13 | 21,055 | 3.88% | 0.09% | 2.07% |
2020 | |||||
Grade 1 | 7 | 21,218 | 3.25% | 0.21% | 1.78% |
Grade 4 | 11 | 19,374 | 3.05% | 0.14% | 1.65% |
Grade 7 | 13 | 20,956 | 3.41% | 0.15% | 1.85% |
2021 | |||||
Grade 1 | 7 | 22,511 | 3.91% | 0.25% | 2.16% |
Grade 4 | 11 | 23,231 | 3.29% | 0.13% | 1.77% |
Grade 7 | 13 | 20,063 | 3.88% | 0.12% | 2.05% |
2019–2021 | |||||
Total students | 189,583 | 3.46% | 0.14% | 1.86% |
Sex | Age | Ishihara Color Test | Gel | |
---|---|---|---|---|
OC1 | F | 61 | miss 1 plate | R/G-G-R/G |
OC2 | F | 40 | normal | R/G-G-X |
OC3 | F | 40 | normal | R/G-G-G |
OC4 | F | 55 | miss 1 plate | R/G-G-G |
RC1 | F | 34 | normal | R/G-G-G |
RC2 | F | 37 | normal | R-R/G-R/G |
RC3 | F | 34 | normal | R-G-R/G |
RC4 | F | 30 | normal | R-R/G-G |
RC5 | F | 31 | normal | R-G-R/G |
RC6 | F | 51 | normal | R-G-R/G |
RC7 | F | 38 | normal | R/G-G-G |
N (n = 73) | F | 37.48 (20~48) | 4 miss 1 plate, 1 miss 2 plate | R-G-G |
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Kuo, H.-K.; Tsao, S.-T.; Wu, P.-C. Prevalence of Congenital Color Vision Deficiency in Southern Taiwan and Detection of Female Carriers by Visual Pigment Gene Analysis. Int. J. Mol. Sci. 2023, 24, 15247. https://doi.org/10.3390/ijms242015247
Kuo H-K, Tsao S-T, Wu P-C. Prevalence of Congenital Color Vision Deficiency in Southern Taiwan and Detection of Female Carriers by Visual Pigment Gene Analysis. International Journal of Molecular Sciences. 2023; 24(20):15247. https://doi.org/10.3390/ijms242015247
Chicago/Turabian StyleKuo, Hsi-Kung, Shih-Ting Tsao, and Pei-Chang Wu. 2023. "Prevalence of Congenital Color Vision Deficiency in Southern Taiwan and Detection of Female Carriers by Visual Pigment Gene Analysis" International Journal of Molecular Sciences 24, no. 20: 15247. https://doi.org/10.3390/ijms242015247