Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins
Abstract
:1. Introduction
2. Intercellular Communication
3. Connexin/Pannexin Expression in the Airway Epithelium
4. Roles of Intercellular Communication in the Well-Polarized Airway Epithelium
5. Speculative Roles of Intercellular Communication in the Regenerating Airway Epithelium
5.1. Connexins and Proliferation
5.2. Connexins, Adhesion, and Migration
5.3. Connexins and Epithelial Integrity
5.4. Connexins, Differentiation and EMT
6. Speculative Roles of Pannexins in the Regenerating Airway Epithelium
7. Concluding Remarks
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Gene | Gene Symbol | Protein Symbol |
---|---|---|
Gap Junction Alpha (GJA) | GJA1 | Cx43 |
GJA3 | Cx46 | |
GJA4 | Cx37 | |
GJA5 | Cx40 | |
GJA8 | Cx50 | |
GJA9 | Cx59 | |
GJA10 | Cx62 | |
Gap Junction Beta (GJB) | GJB1 | Cx32 |
GJB2 | Cx26 | |
GJB3 | Cx31 | |
GJB4 | Cx30.3 | |
GJB5 | Cx31.1 | |
GJB6 | Cx30 | |
GJB7 | Cx25 | |
Gap Junction Gamma (GJC) | GJC1 | Cx45 |
GJC2 | Cx47 | |
GJC3 | Cx30.2 | |
Gap Junction Delta (GJD) | GJD2 | Cx36 |
GJD3 | Cx31.9 | |
GJD4 | Cx40.1 | |
Gap Junction Epsilon (GJE) | GJE1 | Cx23 |
Pannexin (PANX) | PANX1 | Panx1 |
PANX2 | Panx2 | |
PANX3 | Panx3 |
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Badaoui, M.; Chanson, M. Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins. Int. J. Mol. Sci. 2023, 24, 16160. https://doi.org/10.3390/ijms242216160
Badaoui M, Chanson M. Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins. International Journal of Molecular Sciences. 2023; 24(22):16160. https://doi.org/10.3390/ijms242216160
Chicago/Turabian StyleBadaoui, Mehdi, and Marc Chanson. 2023. "Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins" International Journal of Molecular Sciences 24, no. 22: 16160. https://doi.org/10.3390/ijms242216160