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Review

Influence of the Mediterranean Diet on Healthy Aging

by
Maria Carmen Andreo-López
1,†,
Victoria Contreras-Bolívar
1,2,†,
Manuel Muñoz-Torres
1,2,3,4,*,
Beatriz García-Fontana
2,3,5,‡ and
Cristina García-Fontana
1,2,3,‡
1
Endocrinology and Nutrition Unit, University Hospital Clínico San Cecilio, 18016 Granada, Spain
2
Instituto de Investigación Biosanitaria de Granada (Ibs. Granada), 18014 Granada, Spain
3
CIBER on Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, 18012 Granada, Spain
4
Department of Medicine, University of Granada, 18016 Granada, Spain
5
Department of Cell Biology, University of Granada, 18016 Granada, Spain
*
Author to whom correspondence should be addressed.
†
M.C.A.-L. and V.C.-B. contributed equally as first co-authors.
‡
These authors contributed equally to this work and are listed as co-last.
Int. J. Mol. Sci. 2023, 24(5), 4491; https://doi.org/10.3390/ijms24054491
Submission received: 27 January 2023 / Revised: 18 February 2023 / Accepted: 21 February 2023 / Published: 24 February 2023
(This article belongs to the Special Issue The Molecular Links between Nutrients and Aging)
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Abstract

The life expectancy of the global population has increased. Aging is a natural physiological process that poses major challenges in an increasingly long-lived and frail population. Several molecular mechanisms are involved in aging. Likewise, the gut microbiota, which is influenced by environmental factors such as diet, plays a crucial role in the modulation of these mechanisms. The Mediterranean diet, as well as the components present in it, offer some proof of this. Achieving healthy aging should be focused on the promotion of healthy lifestyle habits that reduce the development of pathologies that are associated with aging, in order to increase the quality of life of the aging population. In this review we analyze the influence of the Mediterranean diet on the molecular pathways and the microbiota associated with more favorable aging patterns, as well as its possible role as an anti-aging treatment.
Keywords: aging; Mediterranean diet; molecular pathways; microbiome aging; Mediterranean diet; molecular pathways; microbiome

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MDPI and ACS Style

Andreo-López, M.C.; Contreras-Bolívar, V.; Muñoz-Torres, M.; García-Fontana, B.; García-Fontana, C. Influence of the Mediterranean Diet on Healthy Aging. Int. J. Mol. Sci. 2023, 24, 4491. https://doi.org/10.3390/ijms24054491

AMA Style

Andreo-López MC, Contreras-Bolívar V, Muñoz-Torres M, García-Fontana B, García-Fontana C. Influence of the Mediterranean Diet on Healthy Aging. International Journal of Molecular Sciences. 2023; 24(5):4491. https://doi.org/10.3390/ijms24054491

Chicago/Turabian Style

Andreo-López, Maria Carmen, Victoria Contreras-Bolívar, Manuel Muñoz-Torres, Beatriz García-Fontana, and Cristina García-Fontana. 2023. "Influence of the Mediterranean Diet on Healthy Aging" International Journal of Molecular Sciences 24, no. 5: 4491. https://doi.org/10.3390/ijms24054491

APA Style

Andreo-López, M. C., Contreras-Bolívar, V., Muñoz-Torres, M., García-Fontana, B., & García-Fontana, C. (2023). Influence of the Mediterranean Diet on Healthy Aging. International Journal of Molecular Sciences, 24(5), 4491. https://doi.org/10.3390/ijms24054491

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