Probiotics in Wound Healing

Bădăluță, Valentina Alexandra; Curuțiu, Carmen; Dițu, Lia Mara; Holban, Alina Maria; Lazăr, Veronica

doi:10.3390/ijms25115723

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Probiotics in Wound Healing

by

Valentina Alexandra Bădăluță

^1,2,†

,

Carmen Curuțiu

^1,2,†

,

Lia Mara Dițu

^1,2,

Alina Maria Holban

^1,2,* and

Veronica Lazăr

^1,2

¹

Department of Microbiology, Faculty of Biology, University of Bucharest, 030018 București, Romania

²

Research Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, Romania

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Int. J. Mol. Sci. 2024, 25(11), 5723; https://doi.org/10.3390/ijms25115723

Submission received: 22 April 2024 / Revised: 20 May 2024 / Accepted: 21 May 2024 / Published: 24 May 2024

(This article belongs to the Special Issue Recent Advances in Wound Healing)

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Abstract

Wound infections caused by opportunistic bacteria promote persistent infection and represent the main cause of delayed healing. Probiotics are acknowledged for their beneficial effects on the human body and could be utilized in the management of various diseases. They also possess the capacity to accelerate wound healing, due to their remarkable anti-pathogenic, antibiofilm, and immunomodulatory effects. Oral and topical probiotic formulations have shown promising openings in the field of dermatology, and there are various in vitro and in vivo models focusing on their healing mechanisms. Wound dressings embedded with prebiotics and probiotics are now prime candidates for designing wound healing therapeutic approaches to combat infections and to promote the healing process. The aim of this review is to conduct an extensive scientific literature review regarding the efficacy of oral and topical probiotics in wound management, as well as the potential of wound dressing embedding pre- and probiotics in stimulating the wound healing process.

Keywords: wound healing; probiotic formulations; infection control; wound dressings

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MDPI and ACS Style

Bădăluță, V.A.; Curuțiu, C.; Dițu, L.M.; Holban, A.M.; Lazăr, V. Probiotics in Wound Healing. Int. J. Mol. Sci. 2024, 25, 5723. https://doi.org/10.3390/ijms25115723

AMA Style

Bădăluță VA, Curuțiu C, Dițu LM, Holban AM, Lazăr V. Probiotics in Wound Healing. International Journal of Molecular Sciences. 2024; 25(11):5723. https://doi.org/10.3390/ijms25115723

Chicago/Turabian Style

Bădăluță, Valentina Alexandra, Carmen Curuțiu, Lia Mara Dițu, Alina Maria Holban, and Veronica Lazăr. 2024. "Probiotics in Wound Healing" International Journal of Molecular Sciences 25, no. 11: 5723. https://doi.org/10.3390/ijms25115723

APA Style

Bădăluță, V. A., Curuțiu, C., Dițu, L. M., Holban, A. M., & Lazăr, V. (2024). Probiotics in Wound Healing. International Journal of Molecular Sciences, 25(11), 5723. https://doi.org/10.3390/ijms25115723

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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