Cannabinoids in the Inflamed Synovium Can Be a Target for the Treatment of Rheumatic Diseases
Abstract
:1. Introduction
2. Search Strategy and Manuscript Selection
3. Rheumatic Diseases
3.1. Osteoarthritis
3.2. Rheumatoid Arthritis
3.3. Synovial Tissue Insights into Physiological and Pathological Conditions
3.3.1. Synovial Tissue in OA
3.3.2. Synovial Tissue in RA
4. Cannabinoids
4.1. Endocannabinoids
4.2. Phytocannabinoids
Release Methods and Formulations
4.3. Synthetic Cannabinoids
5. Anti-Inflammatory and Antalgic Effects of Cannabinoids in the OA and RA Synovium
6. ECS Effects on Immune Cells in RA
7. Animal Models
8. Patient’s Expectation
9. Clinical Implications
10. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Roseti, L.; Borciani, G.; Amore, E.; Grigolo, B. Cannabinoids in the Inflamed Synovium Can Be a Target for the Treatment of Rheumatic Diseases. Int. J. Mol. Sci. 2024, 25, 9356. https://doi.org/10.3390/ijms25179356
Roseti L, Borciani G, Amore E, Grigolo B. Cannabinoids in the Inflamed Synovium Can Be a Target for the Treatment of Rheumatic Diseases. International Journal of Molecular Sciences. 2024; 25(17):9356. https://doi.org/10.3390/ijms25179356
Chicago/Turabian StyleRoseti, Livia, Giorgia Borciani, Emanuela Amore, and Brunella Grigolo. 2024. "Cannabinoids in the Inflamed Synovium Can Be a Target for the Treatment of Rheumatic Diseases" International Journal of Molecular Sciences 25, no. 17: 9356. https://doi.org/10.3390/ijms25179356