Aging-Related Metabolome Analysis of the Masseter Muscle in Senescence-Accelerated Mouse-Prone 8
Abstract
:1. Introduction
2. Results
2.1. Body Weight
2.2. Metabolome Analysis
2.2.1. Change in Metabolite Levels between 12 and 40−Week−Old Mice
2.2.2. Change in Metabolite Levels between 12 and 55−Week−Old Mice
2.2.3. Changes in Metabolite Levels between 40 and 55−Week−Old Mice
2.3. Quantitative Analysis of Metabolites Using RT-PCR
3. Discussion
4. Materials and Methods
4.1. Animal Experiment
4.2. Metabolite Extraction and Capillary Electrophoresis–Mass Spectrometry (CE-MS) Metabolome Analysis
4.3. Quantitative Analysis of Gene Expression in the Masseter Muscle with Aging
4.4. Statistical Analyses
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Kato, Y.; Hoshino, T.; Ogawa, Y.; Sugahara, K.; Katakura, A. Aging-Related Metabolome Analysis of the Masseter Muscle in Senescence-Accelerated Mouse-Prone 8. Int. J. Mol. Sci. 2024, 25, 9684. https://doi.org/10.3390/ijms25179684
Kato Y, Hoshino T, Ogawa Y, Sugahara K, Katakura A. Aging-Related Metabolome Analysis of the Masseter Muscle in Senescence-Accelerated Mouse-Prone 8. International Journal of Molecular Sciences. 2024; 25(17):9684. https://doi.org/10.3390/ijms25179684
Chicago/Turabian StyleKato, Yoshiaki, Teruhide Hoshino, Yudai Ogawa, Keisuke Sugahara, and Akira Katakura. 2024. "Aging-Related Metabolome Analysis of the Masseter Muscle in Senescence-Accelerated Mouse-Prone 8" International Journal of Molecular Sciences 25, no. 17: 9684. https://doi.org/10.3390/ijms25179684