Risk Assessment of Fenpropathrin: Cause Hepatotoxicity and Nephrotoxicity in Common Carp (Cyprinus carpio L.)
Abstract
:1. Introduction
2. Results
2.1. Serum Biochemical Parameters
2.2. Histopahology
2.3. Oxidative Stress-Related Parameters in Fish Liver and Kidney
2.4. Inflammation-Related Parameters in Fish Liver and Kidney
2.5. DEGs and qPCR Validation
2.6. Gene Ontology (GO) Analysis of DEGs
2.7. Kyoto Encyclopedia of Genes and Genomes (KEGG) and Protein-Protein Interaction (PPI) Analysis of DEGs
3. Discussion
4. Materials and Methods
4.1. FEN and Common Carp
4.2. Experimental Design and Sample Collection
4.3. Biochemical Parameters Examination
4.4. Transcriptomic Analysis
4.5. Quantitative PCR (qPCR) Analysis
4.6. Histological Analysis
4.7. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Zhu, G.; Liu, Z.; Wang, H.; Mou, S.; Li, Y.; Ma, J.; Li, X. Risk Assessment of Fenpropathrin: Cause Hepatotoxicity and Nephrotoxicity in Common Carp (Cyprinus carpio L.). Int. J. Mol. Sci. 2024, 25, 9822. https://doi.org/10.3390/ijms25189822
Zhu G, Liu Z, Wang H, Mou S, Li Y, Ma J, Li X. Risk Assessment of Fenpropathrin: Cause Hepatotoxicity and Nephrotoxicity in Common Carp (Cyprinus carpio L.). International Journal of Molecular Sciences. 2024; 25(18):9822. https://doi.org/10.3390/ijms25189822
Chicago/Turabian StyleZhu, Gongming, Zhihui Liu, Hao Wang, Shaoyu Mou, Yuanyuan Li, Junguo Ma, and Xiaoyu Li. 2024. "Risk Assessment of Fenpropathrin: Cause Hepatotoxicity and Nephrotoxicity in Common Carp (Cyprinus carpio L.)" International Journal of Molecular Sciences 25, no. 18: 9822. https://doi.org/10.3390/ijms25189822