Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482

Samak, Mostafa; Kues, Andreas; Kaltenborn, Diana; Klösener, Lina; Mietsch, Matthias; Germena, Giulia; Hinkel, Rabea

doi:10.3390/ijms25021058

Open AccessCorrection

Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482

by

Mostafa Samak

^1,2,

Andreas Kues

¹,

Diana Kaltenborn

¹,

Lina Klösener

^1,2,3

,

Matthias Mietsch

^1,2

,

Giulia Germena

^1,2,†

and

Rabea Hinkel

^1,2,3,*,†

¹

Laboratory Animal Science Unit, Leibniz-Institut für Primatenforschung, Deutsches Primatenzentrum GmbH, Kellnerweg 4, 37077 Göttingen, Germany

²

DZHK (German Centre for Cardiovascular Research), Partner Site Göttingen, 37075 Göttingen, Germany

³

Institute for Animal Hygiene, Animal Welfare and Farm Animal Behaviour, University of Veterinary Medicine, 30173 Hannover, Germany

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Int. J. Mol. Sci. 2024, 25(2), 1058; https://doi.org/10.3390/ijms25021058

Submission received: 22 December 2023 / Accepted: 10 January 2024 / Published: 15 January 2024

(This article belongs to the Special Issue Molecular Pathways in Diabetic Cardiomyopathy)

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Versions Notes

In the original publication [1], there was a mistake in Figure 3 as published. The bar graphs in A, C, E, F, H, I, and J were missing the asterisks denoting the statistical significance of the pairwise comparison in correspondence to the p values in the figure legend. The corrected Figure 3 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

Samak, M.; Kues, A.; Kaltenborn, D.; Klösener, L.; Mietsch, M.; Germena, G.; Hinkel, R. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. [Google Scholar] [CrossRef] [PubMed]

Figure 3. Effect and inter-regulation of KLF2 and KLF4 on CMEC function. (A) Analysis of 6 h open wound areas in percentage in MCMECs upon knockdown of Klf2 or Klf4 (n = 4). (B) Bright field images using a Cytation 1 plate reader of MCMEC migration at 0 and 6 h upon knockdown of Klf2. Scale bars equal 1 mm. Quantitative PCR analysis of (C) Klf4 gene expression upon knockdown of Klf2 in MCMECs and (D) Klf2 gene expression upon knockdown of Klf4 in MCMECs, each compared to respective controls (n = 4). (E,F) Quantitative PCR analysis of (E) KLF2 and (F) KLF4 in diabetic HCMECs upon miR-92a inhibition by antagomir (Ant-92a) relative to controls (Ant-Ctrl) (n = 6) and (G) KLF2 and (H) KLF4 in nondiabetic HCMECs upon miR-92a overexpression (pre-92a) relative to controls (pre-Ctrl) (n = 4). (I,J) Quantitative PCR analysis of (I) KLF2 and (J) KLF4 in HUVECs upon miR-92a overexpression (pre-92a) relative to controls (pre-Ctrl). Statistical analyses by unpaired Student’s t-test or by one-way ANOVA (n ≥ 4); * p < 0.05; ** p < 0.01; **** p < 0.0001; ns: not significant.

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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MDPI and ACS Style

Samak, M.; Kues, A.; Kaltenborn, D.; Klösener, L.; Mietsch, M.; Germena, G.; Hinkel, R. Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. Int. J. Mol. Sci. 2024, 25, 1058. https://doi.org/10.3390/ijms25021058

AMA Style

Samak M, Kues A, Kaltenborn D, Klösener L, Mietsch M, Germena G, Hinkel R. Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. International Journal of Molecular Sciences. 2024; 25(2):1058. https://doi.org/10.3390/ijms25021058

Chicago/Turabian Style

Samak, Mostafa, Andreas Kues, Diana Kaltenborn, Lina Klösener, Matthias Mietsch, Giulia Germena, and Rabea Hinkel. 2024. "Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482" International Journal of Molecular Sciences 25, no. 2: 1058. https://doi.org/10.3390/ijms25021058

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Correction: Samak et al. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482

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