Kick-Starting Wound Healing: A Review of Pro-Healing Drugs
Abstract
:1. Introduction
1.1. Normal Wound Healing
1.2. Impaired Wound Healing in Chronic Wounds
2. Current Therapeutics for Wound Healing
2.1. Natural Products
2.1.1. Antibiotics
2.1.2. Silver
2.1.3. Medicinal Honey
2.1.4. Curcumin
2.1.5. Aloe Vera
2.1.6. Birch Bark
2.2. Human-Derived Factors
2.2.1. Mesenchymal Stem Cells
2.2.2. Macrophages
2.2.3. Collagenase
2.2.4. Placental-Derived Products
2.2.5. Autologous Leucocyte/Platelet/Fibrin Patch
2.3. Pharmaceutical Drugs
2.3.1. PDGF (Becapletmin)
2.3.2. Phenytoin
2.3.3. Vitamin A/Retinoids
2.3.4. Hypochlorous Acid
2.3.5. Pentoxifylline
2.3.6. Metformin
3. Conclusions and Future Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Category | Name | Effect on Wound Healing | Commercial Name |
---|---|---|---|
Natural Products | Antibiotics |
| Varied |
Silver sulfadiazine |
| N/A | |
Medicinal Honey |
| MediHoneyTM | |
Curcumin |
| N/A | |
Aloe Vera |
| N/A | |
Birch Bark |
| Episalvan® | |
Human-derived Factors | MSCs |
| N/A |
Collagenase |
| Santyl® | |
Pharmaceutical Drugs | PDGF (Becapletmin) |
| Regranex® |
Phenytoin |
| Dilatin | |
Vitamin A/Retinoids |
| Tretinoin | |
Hypochlorous Acid |
| N/A | |
Pentoxifylline |
| Trental® | |
Metformin |
| Metformin |
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Patenall, B.L.; Carter, K.A.; Ramsey, M.R. Kick-Starting Wound Healing: A Review of Pro-Healing Drugs. Int. J. Mol. Sci. 2024, 25, 1304. https://doi.org/10.3390/ijms25021304
Patenall BL, Carter KA, Ramsey MR. Kick-Starting Wound Healing: A Review of Pro-Healing Drugs. International Journal of Molecular Sciences. 2024; 25(2):1304. https://doi.org/10.3390/ijms25021304
Chicago/Turabian StylePatenall, Bethany L., Kristyn A. Carter, and Matthew R. Ramsey. 2024. "Kick-Starting Wound Healing: A Review of Pro-Healing Drugs" International Journal of Molecular Sciences 25, no. 2: 1304. https://doi.org/10.3390/ijms25021304