Novel Epigenetic Modifiers of Histones Presenting Potent Inhibitory Effects on Adenoid Cystic Carcinoma Stemness and Invasive Properties
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. Cell Line and Culture Conditions
4.2. Histone Modifiers Library and High-Throughput Screening (HTS)
4.3. Immunofluorescence
4.4. Flow Cytometry
4.5. Scratch Assay
4.6. Tumorsphere Assay
4.7. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Pina, P.S.S.; Jang, Y.; Emerick, C.; Scarini, J.F.; Sousa, S.C.O.M.; Squarize, C.H.; Castilho, R.M. Novel Epigenetic Modifiers of Histones Presenting Potent Inhibitory Effects on Adenoid Cystic Carcinoma Stemness and Invasive Properties. Int. J. Mol. Sci. 2024, 25, 1646. https://doi.org/10.3390/ijms25031646
Pina PSS, Jang Y, Emerick C, Scarini JF, Sousa SCOM, Squarize CH, Castilho RM. Novel Epigenetic Modifiers of Histones Presenting Potent Inhibitory Effects on Adenoid Cystic Carcinoma Stemness and Invasive Properties. International Journal of Molecular Sciences. 2024; 25(3):1646. https://doi.org/10.3390/ijms25031646
Chicago/Turabian StylePina, Paulo S. S., Yeejin Jang, Carolina Emerick, João Figueira Scarini, Suzana C. O. M. Sousa, Cristiane H. Squarize, and Rogerio M. Castilho. 2024. "Novel Epigenetic Modifiers of Histones Presenting Potent Inhibitory Effects on Adenoid Cystic Carcinoma Stemness and Invasive Properties" International Journal of Molecular Sciences 25, no. 3: 1646. https://doi.org/10.3390/ijms25031646