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Molbank
Volume 2021
Issue 3
10.3390/M1268
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Short Note

(±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol

by
Milenca Mariana Vorga
and
Valentin Badea
*
Department of Applied Chemistry and Organic and Natural Compounds Engineering, Politehnica University Timisoara, Carol Telbisz 6, 300001 Timisoara, Romania
*
Author to whom correspondence should be addressed.
Molbank 2021, 2021(3), M1268; https://doi.org/10.3390/M1268
Submission received: 28 May 2021 / Revised: 12 July 2021 / Accepted: 2 August 2021 / Published: 6 August 2021
(This article belongs to the Section Organic Synthesis and Biosynthesis)
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Abstract

The novel racemic secondary alcohol (±)-2-{[4-(4-bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol (12) has been successfully synthesized through S-alkylation of 4-(4-bromophenyl)-5-phenyl-4H-1,2,4-triazole-3-thiol (10) in alkaline medium with 2-bromo-1-phenylethanone followed by reduction of the corresponding ketone 11. All the synthesized compounds were characterized by IR, 1D (1H, 13C, DEPT135) and 2D (1H-1H, 1H-13C and 1H-15N) NMR spectroscopy, elemental analysis and HRMS spectrometry.
Keywords: 1,2,4-triazole-3-thiol; S-alkylation; secondary heterocyclic alcohol; racemic 1,2,4-triazole-3-thiol; S-alkylation; secondary heterocyclic alcohol; racemic

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MDPI and ACS Style

Vorga, M.M.; Badea, V. (±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol. Molbank 2021, 2021, M1268. https://doi.org/10.3390/M1268

AMA Style

Vorga MM, Badea V. (±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol. Molbank. 2021; 2021(3):M1268. https://doi.org/10.3390/M1268

Chicago/Turabian Style

Vorga, Milenca Mariana, and Valentin Badea. 2021. "(±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol" Molbank 2021, no. 3: M1268. https://doi.org/10.3390/M1268

APA Style

Vorga, M. M., & Badea, V. (2021). (±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol. Molbank, 2021(3), M1268. https://doi.org/10.3390/M1268

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