Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery
Abstract
:1. Introduction
2. Two-Dimensional MNP Navigation System
3. Two-Dimensional AM MPI Signal and Image Reconstruction
3.1. Generation of an FFP and Its Movement in the FOV
3.2. Low-Amplitude, High-Frequency Excitation Field
3.3. Total Magnetic Field
3.4. Magnetization of Particles
3.5. Signal Produced by 2D AM MPI
3.6. Signal Processing
3.7. Reconstruction of 2D AM MPI
4. Results and Discussion
4.1. Experimental Setup
4.2. Two-Dimensional Real-Time AM MPI Monitoring
4.3. Discussions for the Developed 2D MPI System
5. Conclusions
Supplementary Materials
Supplementary File 1Acknowledgments
Author Contributions
Conflicts of Interest
References
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Turns | Inner Diameter | Outer Diameter | Coil Length | Wire | |
---|---|---|---|---|---|
Actuation/selection-drive coil (x-axis) | 5000 | 0.070 m | 0.190 m | 0.070 m | 1 mm copper wire |
Actuation/drive coil (y-axis) | 260 | 0.040 m | 0.126 m | 0.030 m | Litz wire |
Receive coil | 400 | 0.042 m | Single layer | 0.060 m | Litz wire |
Cancellation coil | 200 | 0.042 m | Single layer | 0.015 m | Litz wire |
Excitation coil | 44 | 0.050 m | Single layer | 0.110 m | Litz wire |
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Le, T.-A.; Zhang, X.; Hoshiar, A.K.; Yoon, J. Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery. Sensors 2017, 17, 2050. https://doi.org/10.3390/s17092050
Le T-A, Zhang X, Hoshiar AK, Yoon J. Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery. Sensors. 2017; 17(9):2050. https://doi.org/10.3390/s17092050
Chicago/Turabian StyleLe, Tuan-Anh, Xingming Zhang, Ali Kafash Hoshiar, and Jungwon Yoon. 2017. "Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery" Sensors 17, no. 9: 2050. https://doi.org/10.3390/s17092050